Evaluation of a Poly(Lactic-Co-Glycolic) Acid-Coated β-Tricalcium Phosphate Bone Substitute for Alveolar Ridge Preservation: Multicenter Randomized Control Trial
| dc.contributor.advisor | Saito, Hanae | |
| dc.contributor.author | West, Brandon M. | |
| dc.date.accessioned | 2019-06-19T16:13:29Z | |
| dc.date.available | 2019-06-19T16:13:29Z | |
| dc.date.issued | 2019 | |
| dc.date.updated | 2019-06-17T19:17:37Z | |
| dc.description | 2019 | |
| dc.description | Biomedical Sciences-Dental School | |
| dc.description | University of Maryland , Baltimore | |
| dc.description | M.S. | |
| dc.description.abstract | Purpose: The aim of this study was to determine whether the efficacy of PLGA-β-TCP in Alveolar Ridge Preservation (ARP) with histological analysis of the extraction socket following four months healing was similar to FDBA + CP as the control. Materials and Methods: 45 adult patients in this multicenter randomized controlled clinical trial were randomly assigned into treatment group A [PLGA-β-TCP] or group B [FDBA + CP] for ARP of a single extraction socket. Results: 45 bone core samples were harvested. Vital bone was present in intimate contact with the surface of β-TCP graft particles. Histologic measurements revealed no statistically significant difference between the test and control groups in percent vital bone after four months healing. Conclusion: This investigation demonstrated the similar efficacy of PLGA- β-TCP to FDBA as a bone substitute in ARP. | |
| dc.identifier.uri | http://hdl.handle.net/10713/9579 | |
| dc.language.rfc3066 | en | |
| dc.subject | alveolar ridge preservation | en_US |
| dc.subject | PLGA | en_US |
| dc.subject | β-TCP | en_US |
| dc.subject | beta tricalcium phosphate | en_US |
| dc.subject.mesh | Bone Substitutes | en_US |
| dc.subject.mesh | Polylactic Acid-Polyglycolic Acid Copolymer | en_US |
| dc.title | Evaluation of a Poly(Lactic-Co-Glycolic) Acid-Coated β-Tricalcium Phosphate Bone Substitute for Alveolar Ridge Preservation: Multicenter Randomized Control Trial | en_US |
| dc.type | dissertation | en_US |
| dspace.entity.type | Publication | |
| refterms.dateFOA | 2019-06-19T16:13:30Z |