Now showing items 1-20 of 13072

    • ICTR at Medical Grand Rounds: Harnessing our Common African Genome to Improve Health Globally

      Wonkam, Ambroise (2022-06-29)
      Wonkam discusses the imperative need to research African genomic variation.
    • ICTR at Medical Grand Rounds: Moving Fruits, Vegetables, Nuts, and Beans through the Translational Research Pathway

      Miller, Edgar Pete, III, MD, PHD (2021-09-01)
      Miller discusses the impact of diet modification on blood pressure, and the impact of providing health foods and advice on health food intake.
    • ICTR Enrichment Series: Opportunities for Healthcare Research Using Administrative Data: An Introduction to the IQVIATM Health Plans Claims Data

      dosReis, Susan; Onukwugha, Eberechukwu (2019-08-13)
      dosRein and Onukwugha overview IQVIA Health Plan Claims Data, ICTR support for projects using IQVIA data, steps to obtain ICTR support, and discuss an example project.
    • IGS Insider Newsletter 2024

      University of Maryland, Baltimore. School of Medicine., 2024
    • ICTR Enrichment Series: Community Based Participatory Research: Challenges and Rewards

      Rosenthal, Robert E.; Doherty, Julie, D.M., M.S.N., R.N., C.I.P, C.C.E.P. (2022-02-24)
      Drs. Rosenthal and Doherty discuss Community Based Participatory Research (CBPR), a collaborative approach to research that involves all stakeholders throughout the research process.
    • ICTR Enrichment Series: Innovative Ways Using Social Media Platforms for Research Participant Recruitment and Participation

      Breman, Rachel B.; Craddock, Jaih (2022-03-08)
      Dr. Rachel Blankstein Breman discusses using social media for recruitment research and Dr. Jaih Craddock discusses text-based recruitment.
    • ICTR Enrichment Series: Patient-Centered Research: Increase Access and Impact of Clinical Research and Trials to Reduce Health Disparities

      Jain, Praduman (2023-12-12)
      Discussion Synopsis: Jain talks about his experience with several research programs, small and large, that are utilizing these innovative, evidence-based digital tools and resources to conduct patient powered/patient centered precision research. These tools are scientifically proven and have been shown to reduce barriers to clinical research. Jain also talks about how ICTR can build capacity for successful pragmatic clinical trials, investigator-initiated studies, and industry clinical trials, through digital tools, training, and processes. Jain highlights a few research programs such as the NIH All of Us, a large longitudinal study, that has successfully achieved high, multi-year RETENTION through community engagement.
    • ICTR Enrichment Series: Creating a centralized social media service to raise awareness about research opportunities and to grow our volunteer registry at the University of Michigan

      Connally, Lisa (2023-11-14)
      Discussion synopsis: While exploring ways to assist study teams expand recruitment efforts into traditionally underserved and underrepresented communities, the Participant Recruitment Team began to research paid, targeted social media advertising. This merging recruitment strategy seemed like a viable option, but we found that most study teams didn’t feel they had the expertise or the bandwidth to explore this method. A survey of researchers on campus found that over 70% said they would utilize social media as a recruitment strategy if someone else created the campaign and monitored the analytics for them. Connally discusses how a centralized service was created to assist with social media advertising at the University of Michigan.
    • ICTR Enrichment Series: NHLBI Catalyze Program: Providing Bridge from Basic to Clinical Research

      Shapiro, Paul, Ph.D. (2023-09-12)
      This Enrichment seminar covers the discovery of novel kinase inhibitors that mitigate pathological airway remodeling associated with asthma. Dr. Shapiro discusses how ICTR resources helped generate preliminary data and NIH funding through the R61/R33 Catalyze program at the National Heart, Lung, and Blood Institute. The talk also covers the goals of the Catalyze program and its role in promoting the development of new therapies and entrepreneurial activities. Dr. Shapiro’ concludes with ICTR pilot grant and micro-grant opportunities as well as ICTR cores of services available to researchers.
    • ICTR Enrichment Series: Navigating the NIH Data Management and Sharing Policy: Tools, Strategies, and Best Practices

      Yarnell, Amy M.; Fraticelli-Rodriguez, Irmarie (2023-07-11)
      The Data Services Librarians from the Health Sciences and Human Services Library (HSHSL) provide an overview of the new NIH Data Management and Sharing Policy (DMSP) and resources available to help comply with requirements. The seminar covers the free online application DMPTool, strategies for choosing a data repository, and insights into data sharing best practices.
    • ICTR Enrichment Series: Research with Impact! Dissemination and Implementation(D&I) Science to Inform Clinical Care and Prevention Strategies: from Data to Action

      Shaya, Fadia T. (2023-05-09)
      In this talk, Dr. Shaya presents cases of D&I in clinical and translational research, in the context of drug prescribing, and substance use prevention. She showcases success stories and dissemination products. She presents translational science methods, including rigorous needs assessment, data sourcing and analysis, dissemination of findings and as well as strategies for supporting successful implementation in clinical and public health practice.
    • ICTR Enrichment Series: Overview of Drug Development and UMB Resources

      Quraishi, Rana (2023-03-14)
      In this talk, Dr. Quraishi demystifies the process of drug development given that it takes seven to ten years, costs millions of dollars, there is no return on investment until the drug is approved, and failure rates are very high. Additionally, there is a complex regulatory pathway and a lot of competition. Dr. Quraishi discusses how all this is managed. She spends the second part of the talk discussing services and support the New Ventures group offers and is developing for those interested in the commercialization of their discovery.
    • ICTR Enrichment Series: Towards Building a Clinically-Inspired Ultrasound Innovation Hub: Design, Development and Clinical Validation of Ultrasound Probes for Imaging, Therapeutics, Sensing and Other Applications

      Manbachi, Amir (2023-01-10)
      Ultrasound is a relatively established modality with a number of exciting, yet not fully explored applications, ranging from imaging and image-guided navigation to tumor ablation, neuromodulation, piezoelectric surgery, and drug delivery. In this talk, Dr. Manbachi discusses some of his ongoing projects aiming to address low-frequency neuromodulation, minimally invasive ablation of neuro-oncology and implantable sensors for spinal cord blood flow measurements.
    • ICTR Enrichment Series: "Clinical Utility of Testing Symptomatic Women for Both Sexually Transmitted Infections (STIs) & Vaginitis” and “Cervical Cancer Screening in the Era of the Covid-19 Pandemic

      Broache, Molly; Vaughan, Laurence M. (2022-11-08)
      Two presentations by BD Innovation Center staff. The BD Innovation Center recently opened a state-of-the-art facility at the University of Maryland BioPark that will give students and researchers access to new laboratory space and advanced diagnostic tools. The center’s goal is to help streamline clinical laboratory workflows and improve patient care by expanding basic diagnostic knowledge, developing new diagnostic capabilities, and shaping the future of diagnostics by allowing students and researchers to provide real-world feedback on early diagnostic concepts.
    • ICTR Enrichment Series: Adaptive Community Engagement in Dementia Care Research: Navigating Disease Progression to Collaboratively Advance Science

      Lepore, Michael, Ph.D. (2022-09-13)
      Dr. Lepore introduces an overview of challenges faced in maintaining community engagement and tactics used to contend with progressive cognitive impairment experienced by people living with dementia (PLWD) are described, and the impacts of PLWD engagement on the investigator’s research program, including newly funded community based participatory research with PLWD.
    • SINI 2023: Keynote: Panel Discussion- The Value of Informatics and the Informatician in Healthcare

      Young, Teri; Wellbaum, Donna; Penoza, Carleen; Swietlik, Marguerite (2023-07-20)
    • Smoking Cessation Among People With Severe Mental Illness

      Alghzawi, Hamzah Mohammad; Storr, Carla L. (2019)
      Introduction: People living with mental illnesses have a high rate of smoking and make up over half of those dependent on nicotine. A considerable body of research has shown that social support, stressful life events (SLE), receiving help for tobacco/nicotine use, intention to quit, and smoking use-related factors are associated with smoking cessation in the general population. Yet, little is known about these factors among people with severe mental illness (SMI). Purpose: This study aims to: 1) examine gender differences in the interrelations among social support, SLEs, and smoking cessation, 2) estimate the probability of remission from NUD by type of help/services received for tobacco/nicotine use (pharmacological, non-pharmacological, and both), and 3) estimate gender and racial/ethnic differences in the probability of smoking cessation among those with a history of intention to quit. Methods: A sample of 4610 people with SMI and a history of tobacco/nicotine use were identified in a public limited dataset of the 2012-2013 National Epidemiologic Survey on Alcohol and Related Conditions (NESARC-III). Four mediation and moderated mediation models were used in the first manuscript, whereas survival analyses were used in the second and third manuscripts. All analyses took into account the complex sampling design and controlled for possible confounders (i.e. sociodemographic characteristics) and covariates (i.e. comorbidity with another mental illness). Results: Total, appraisal, and tangible support in females exerted indirect effects on improving smoking cessation via decreased SLEs (total=.0094, appraisal=.0229, tangible=.0298; p<.05). The probability of remission from NUD was higher among those who received non-pharmacological services (28.5%, HR=1.95, p<.05) or those who received both services (19.6%, HR=1.52, p<.05) compared to those who only had pharmacological services (17.6%). Among those with a history of intention to quit, 31.7% had stopped. The probability of smoking cessation was highest for Hispanic females (HR=2.07, p<.05), non-Hispanic other females (HR=1.59, p<.05), non-Hispanic other males (HR=1.45, p<.05), Hispanic males (HR=1.40, p<.05), and non-Hispanic Black females (HR=1.35, p<.05) compared to non-Hispanic Black males. Conclusion: A greater understanding of subgroup differences and the correlates of smoking cessation among tobacco/nicotine users with SMI can enhance efforts to design and implement smoking cessation programs for people with SMI.
    • Telling Baltimore Stories Through Data

      Yarnell, Amy M.; Knott, Cheryl; Little, Ryan; Sadler, James (2024-02-15)
    • PA Education and Practice in Maryland: Current Status, Opportunities and Challenges

      PALLA (Physician Assistant Leadership and Learning Academy) (2024-01)
      Physician assistants/associates have become a well-established component of the US health care work force. In Maryland, the PA profession is flourishing with more than 3600 PAs in active clinical practice and 5 operational PA education programs. A growth rate of approximately 40% has been projected between 2018-2028. The Physician Assistant Leadership and Learning Academy (PALLA), based at the University of Maryland, Baltimore with funding from the state, was created in 2019 to advance PA education, research, policy, and practice in the state. Consistent with this mission, PALLA regularly conducts an environmental scan to ascertain current opportunities and challenges facing the PA profession in the state. In fall of 2023, PALLA undertook an examination of the status of the profession and the state’s PA educational programs. For this report, PALLA conducted a series of semi-structured interviews with Maryland PA program faculty, program leaders, and deans. PALLA also analyzed secondary data from both local and national agencies. Several themes consistently arose from this analysis; among them were a strong demand among applicants, PA graduates staying local, concerns regarding program leadership and faculty stability, challenges in the development of effective student remediation processes, and the issue of clinical site and preceptor shortages. Additional areas of concern identified by Maryland PA program leadership and faculty were issues related to accreditation, levels of institutional support, faculty turnover and workload, sufficiency of support, and lack of diversity among faculty and students. There was a desire among interviewees for increased collaboration between PA programs and other health professions. At a practice level, PAs are making a strong impact in various clinical settings and the demand currently outweighs the supply in Maryland. However, scope of practice regulations remains a major barrier in maximizing PA value in Maryland. Based on current opportunities and challenges identified, we present a series of specific and detailed recommendations that we hope will stimulate discussion among various stakeholders while advancing the quality of PA education, policy, and practice in Maryland