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Improving Delays in Antibiotic Administration in Emergency Department Boarder Patients with Sepsis

Authors
Wetzel, Grace
Date
2025-05
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DNP Project
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Problem: The practice problem takes place in the Emergency Department (ED) of a large urban academic hospital where there are over 400 automated sepsis alerts and approximately 40 sepsis related patient deaths per month within the facility. A standardized sepsis bundle was introduced to the facility in 2022 for admitted in-patients, but the process of requiring the Quick Sepsis- related Organ Failure Assessment (qSOFA) as part of the bundle has not been standardized for the admitted medical/surgical (med/surg) patients boarding in the ED. This lack of standardization has caused significant delays in the care specifically antibiotic administration. Purpose: The purpose of this quality improvement project was to implement the qSOFA scoring tool to improve antibiotic administration time for adult ED med/surg boarder patients with suspected sepsis. Methods: The data was collected through the automated Tableau system within the hospital’s electronic health record (EHR) and then entered into REDCap for tabulation. The data measured included the total number of qSOFA forms completed, time between sepsis alert generation and antibiotic administration, if applicable, and Mortality Index. Eligible patients included all admitted in-patients boarding within the ED who alerted for sepsis. Results: During the fifteen weeks of the project, 33 qSOFA forms out of 36 alerts were completed. Timing for sepsis bundle completion ranged from 5 to 601 minutes, and median antibiotic administration time improved to 75.5 minutes. Limitations included not every patient with a sepsis alert was ordered antibiotics leading to a smaller data pool. Conclusions: These findings suggest utilizing the qSOFA score within the med/surg ED boarder patients who have alerted for sepsis improved antibiotic administration from a median of 124 minutes to 75.5 minutes. This project therefore suggests compliance to a standardized bundle leads to improved antibiotic administration timeliness. Keywords: sepsis, qSOFA, antibiotic administration, EDBO patients, sepsis bundle

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