Problem: Critical information was often missed in nursing handoff among patients transferred from the Post Anesthesia Care Unit (PACU) to the inpatient Surgical Care Unit (SCU) at a large urban pediatric hospital. Over one year, ten incident reports highlighted communication failures between PACU and SCU. An audit of 20 handoffs revealed frequent omissions in five key areas: patient acuity (70%), review of systems (55%), line reconciliation (75%), inpatient care orders (45%), and opportunities to ask questions (95%), leaving SCU nurses unprepared to provide safe, effective care. Purpose: This quality improvement project aimed to implement a validated, evidence-based handoff tool, I-PASS (illness severity, patient summary, action list, situation awareness and contingency plans, and synthesis by receiver), to reduce missed information during transitions of care. The 15-week initiative was implemented to improve the quality and safety of care for post-operative pediatric patients. Methods: The I-PASS handoff tool was implemented following education with 49 SCU nurses. SCU nurses used blank I-PASS templates during handoff report from PACU, then completed anonymous surveys indicating whether the five critical elements were included. Results: Over the 15-week implementation, SCU nurse utilized the I-PASS template 87 times during PACU to SCU handoff. The inclusion of each pertinent element in handoff when the I-PASS template was used are: patient acuity (93.1%), review of systems (82.8%), line reconciliation (96.6%), inpatient care orders (80.5%), and opportunity to ask questions (97.7%). Conclusions: The results show a positive increase in the frequency of inclusion of the five pertinent elements of handoff after implementing a standardize I-PASS template. The results correlate with the evidence that utilizing I-PASS while receiving nursing handoff on a post-operative pediatric patient can reduce the frequency of missed information critical for providing safe nursing care.