Problem: A high-volume adult post-surgical unit consistently fell below the 50% Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) benchmark for communication on medication side effects from July 2021 to June 2023. Inadequate patient education on medication side effects has been linked to adverse outcomes such as readmissions, poor adherence, and drug-related complications. The lack of a standardized protocol for medication education delivery exacerbates these issues, particularly during discharge. Purpose: This quality improvement (QI) project aimed to enhance patient understanding of medication side effects through the implementation of the Teach-Back Method (TBM) and Simplified Information Leaflets (SILs). Standardizing this evidence-based intervention sought to improve patient education, reduce medication-related complications, and enhance HCAHPS scores. Methods: 35 registered nurses (RNs) responsible for inpatient and discharge education completed an education module on TBM and SILs before data collection. Intervention adherence was tracked via the RN Discharge Survey Sheet with data stored in REDCap. Over 15 weeks, the QI Project Lead (QI-PL) conducted biweekly site visits, collaborating with nursing leadership and staff. Weekly data analysis monitored intervention adherence with a goal of 100%. Results:71% of nursing staff completed the mandatory educational module. The average adherence rate for TBM was 39.63%, and SIL usage was 39.42%. Conclusions: Integrating TBM and SILs demonstrates potential for improving medication-related outcomes and health literacy. Future efforts should enhance staff adherence, continued evaluation of patient-centered outcomes, and long-term sustainability. Keywords: patient education, Teach-Back Method, medication side effects, Simplified Information Leaflets, quality improvement, HCAHPS, nursing