With the increase in community-engaged research (CEnR) involving patients and community members as advisors versus “human subjects,” the line between Human Subjects Research and Non -Human Subjects Research (NHSR) is sometimes blurred. Moreover, many CEnR studies haveboth a NHSR phase (e.g. planning with Advisory Board) and a subsequent investigational phase during which a full IRB protocol for Human Subjects Research is needed. This session is a great opportunity for researchers to learn about the nuances of when community members are advisors vs. human subjects in research.