Report on eighth WHO meeting on development of influenza vaccines that induce broadly protective and long-lasting immune responses: Chicago, USA, 23–24 August 2016
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Abstract
In August 2016, the World Health Organization (WHO) convened the “Eighth meeting on development of influenza vaccines that induce broadly protective and long-lasting immune responses” to discuss the regulatory requirements and pathways for licensure of next-generation influenza vaccines, and to identify areas where WHO can promote the development of such vaccines. Participants included approximately 120 representatives of academia, the vaccine industry, research and development funders, and regulatory and public health agencies. They reviewed the draft WHO preferred product characteristics (PPCs) of vaccines that could address prioritized unmet public health needs and discussed the challenges facing the development of such vaccines, especially for low- and middle-income countries (LMIC). They defined the data desired by public-health decision makers globally and explored how to support the progression of promising candidates into late-stage clinical trials and for all countries. This report highlights the major discussions of the meeting. © 2017 World Health Organization.Sponsors
The authors acknowledge the contributions of the Centers for Disease Control and Prevention ( CK14-1402 ), which provides financial support to the World Health Organization Initiative for Vaccine Research. The authors also acknowledge contributions of the US National Institutes of Health ( U01AI108543-01 ), which provided grant funding for partial support of this meeting.Keyword
InfluenzaNextgeneration influenza vaccine
Pandemic influenza vaccine
Seasonal influenza vaccine
Universal influenza vaccine
Vaccine development
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