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    Recommendations for toxicological investigation of drug-impaired driving and motor vehicle fatalities-2017 update

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    Author
    Logan, B.K.
    D'Orazio, A.L.
    Mohr, A.L.A.
    Date
    2018
    Journal
    Journal of Analytical Toxicology
    Publisher
    Oxford University Press
    Type
    Article
    
    Metadata
    Show full item record
    See at
    https://dx.doi.org/10.1093/jat/bkx082
    Abstract
    This report describes the outcomes of a process undertaken to review and update the National Safety Council's Alcohol, Drugs and Impairment Division's recommendations for the toxicological investigation of suspected alcohol and drug-impaired driving cases and motor vehicle fatalities. The updates to the recommendations are made based on a survey of practices in laboratories in the USA and Canada performing testing in these cases, consideration of existing epidemiological crash and arrest data, current drug use patterns, and practical considerations of widely available technology platforms in laboratories performing this work. The final recommendations updates are derived from a consensus meeting of experts recruited from survey respondents and the membership of the National Safety Council's Alcohol, Drug and Impairment Division. The principal changes in this round of recommendations include removal of butalbital, phenobarbital, and phencyclidine from Tier I (mandatory) to Tier II (optional) due to changes in prevalence. In addition, buprenorphine, fentanyl, tramadol, and their metabolites were moved from Tier II to Tier I due to increased prevalence and concerns about their potential for causing impairment. In addition, screening and confirmatory cutoffs for the oral fluid scope were further refined. Other additions were made to the list of Tier II compounds including fentanyl analogs (e.g., acetylfentanyl, butyrylfentanyl, furanylfentanyl, etc), mitragynine, novel opioids (e.g., MT-45, U- 47700), atypical antipsychotics, and novel benzodiazepines (e.g., clonazolam, flubromazolam, etc). Copyright The Author 2017. Published by Oxford University Press. All rights reserved.
    Sponsors
    Funding for this project was provided by the National Safety Council under contract # DTNH22-15-H-00473.
    Keyword
    National Safety Council. Alcohol, Drugs, and Impairment Division
    toxicological investigation
    Traffic fatalities
    Drugged driving
    Identifier to cite or link to this item
    https://www.scopus.com/inward/record.uri?eid=2-s2.0-85043334840&doi=10.1093%2fjat%2fbkx082&partnerID=40&md5=fd10815321e33504f0f49bfa855ae22b; http://hdl.handle.net/10713/9483
    ae974a485f413a2113503eed53cd6c53
    10.1093/jat/bkx082
    Scopus Count
    Collections
    UMB Open Access Articles 2018

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