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dc.contributor.authorMori, H.
dc.contributor.authorJinnouchi, H.
dc.contributor.authorDiljon, C.
dc.date.accessioned2019-06-05T18:28:12Z
dc.date.available2019-06-05T18:28:12Z
dc.date.issued2018
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85048968939&doi=10.2217%2ffca-2017-0103&partnerID=40&md5=32a19e81bc76978b92766305a262d236
dc.identifier.urihttp://hdl.handle.net/10713/9386
dc.description.abstractThe COBRA-PzF™ (CeloNova BioSciences, Inc., TX, USA) is a new type of coronary stent composed of a cobalt chromium metallic backbone surrounded by a nanothin layer of Polyzene-F (PzF) without any added drug. Evidence from basic studies supports antithrombotic and anti-inflammatory properties for the PzF surface coating. Preclinical studies support the thromboresistance of PzF-coated surfaces and clinical studies have shown good outcomes for patients receiving this device with very low rates of stent thrombosis. COBRA-PzF may be especially useful in patients at high risk for bleeding. Ongoing clinical trials will determine whether shortening the duration of dual antiplatelet therapy to less than 1 month is feasible and these data may represent a new paradigm with regards to patients at high risk for bleeding. Copyright 2018 Future Medicine Ltd.en_US
dc.description.urihttps://dx.doi.org/10.2217/fca-2017-0103en_US
dc.language.isoen-USen_US
dc.publisherFuture Medicine Ltd.en_US
dc.relation.ispartofFuture Cardiology
dc.subjectbleedingen_US
dc.subjectdrug-eluting stenten_US
dc.subjectpolymeren_US
dc.subjectstenten_US
dc.subjectstent thrombosisen_US
dc.titleA new category stent with novel polyphosphazene surface modificationen_US
dc.typeArticleen_US
dc.identifier.doi10.2217/fca-2017-0103
dc.identifier.pmid29582698


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