Date
2019-05-09Journal
Neural Regeneration ResearchPublisher
Wolters Kluwer Medknow PublicationsType
Article
Metadata
Show full item recordAbstract
Neuroinflammation is initiated as a result of traumatic brain injury and can exacerbate evolving tissue pathology. Immune cells respond to acute signals from damaged cells, initiate neuroinflammation, and drive the pathological consequences over time. Importantly, the mechanism(s) of injury, the location of the immune cells within the brain, and the animal species all contribute to immune cell behavior following traumatic brain injury. Understanding the signals that initiate neuroinflammation and the context in which they appear may be critical for understanding immune cell contributions to pathology and regeneration. Within this paper, we review a number of factors that could affect immune cell behavior acutely following traumatic brain injury. © 2019 Medknow.Sponsors
The work was supported by the Department of Veterans Affairs, USA (Merit Review I01-RX001097 & I01-BX003748).Rights/Terms
Attribution-NonCommercial-ShareAlike 3.0 United StatesKeyword
acuteadenosine 5′-triphosphoate
calcium
cytokines
diffuse brain injury
glutamate
inflammation
macrophage
microglia
neuroinflammation
traumatic brain injury
Identifier to cite or link to this item
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85065827019&origin=inward; http://hdl.handle.net/10713/9326ae974a485f413a2113503eed53cd6c53
10.4103/1673-5374.255958
Scopus Count
Collections
The following license files are associated with this item:
- Creative Commons
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-ShareAlike 3.0 United States