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    Novel self-etch adhesive with antibacterial and protein-repellent functions to prevent enamel demineralization

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    Author
    Wang, B.
    Zhang, N.
    Wang, X.
    Date
    2018
    Journal
    Dental Materials Journal
    Publisher
    Japanese Society for Dental Materials and Devices
    Type
    Article
    
    Metadata
    Show full item record
    See at
    https://dx.doi.org/10.4012/dmj.2017-422
    Abstract
    Enamel demineralization is the most undesired side-effect of fixed orthodontic treatments. This study were to develop a novel adhesive that is self-etching instead of using the traditional etching method, and to form a sealant on the enamel to prevent demineralization. 2-methacryloyloxyethyl phosphorylcholine (MPC) and quaternary ammonium dimethylaminohexadecyl methacrylate (DMAHDM) were mixed into a self-etch adhesive (Adper Easy One, 3M, St. Paul, MN, USA; referred to as AEO). Enamel shear bond strength (SBS) was measured. Protein adsorption onto the resins was measured. An oral microcosm biofilm model with saliva was tested. Incorporation of 7.5% MPC and 5% DMAHDM into AEO did not reduce the SBS (p>0.1). AEO with 7.5% MPC+5% DMAHDM had protein adsorption that was only 1/18 that of AEO control. AEO with 7.5% MPC+5% DAMHDM had much stronger antibacterial properties (p<0.05). In conclusion, the new self-etch adhesive with MPC and DAMHDM greatly reduced protein adsorption and inhibited biofilm viability. Copyright 2018, Japanese Society for Dental Materials and Devices. All rights reserved.
    Sponsors
    This study was supported by Natural Science Foundation of China NSFC 81500879 (NZ), Beijing Municipal Administration of Hospitals' Youth Program QML20161501 (NZ), Beijing Municipal Science and Technology Commission Z151100003915137 (YB), Beijing Municipal Hospitals' Program ZYLX201703 (YB), NIH R01 DE17974 (HX) and a Seed Grant (HX) from the University of Maryland School of Dentistry.
    Keyword
    Antibacterial property
    Enamel demineralization
    Mechanical property
    Protein repellent
    Self-etch adhesive
    Identifier to cite or link to this item
    https://www.scopus.com/inward/record.uri?eid=2-s2.0-85061893126&doi=10.4012%2fdmj.2017-422&partnerID=40&md5=e42fbd8eb3a0017bcb591353d118d24c; http://hdl.handle.net/10713/9315
    ae974a485f413a2113503eed53cd6c53
    10.4012/dmj.2017-422
    Scopus Count
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