Novel self-etch adhesive with antibacterial and protein-repellent functions to prevent enamel demineralization
JournalDental Materials Journal
PublisherJapanese Society for Dental Materials and Devices
MetadataShow full item record
AbstractEnamel demineralization is the most undesired side-effect of fixed orthodontic treatments. This study were to develop a novel adhesive that is self-etching instead of using the traditional etching method, and to form a sealant on the enamel to prevent demineralization. 2-methacryloyloxyethyl phosphorylcholine (MPC) and quaternary ammonium dimethylaminohexadecyl methacrylate (DMAHDM) were mixed into a self-etch adhesive (Adper Easy One, 3M, St. Paul, MN, USA; referred to as AEO). Enamel shear bond strength (SBS) was measured. Protein adsorption onto the resins was measured. An oral microcosm biofilm model with saliva was tested. Incorporation of 7.5% MPC and 5% DMAHDM into AEO did not reduce the SBS (p>0.1). AEO with 7.5% MPC+5% DMAHDM had protein adsorption that was only 1/18 that of AEO control. AEO with 7.5% MPC+5% DAMHDM had much stronger antibacterial properties (p<0.05). In conclusion, the new self-etch adhesive with MPC and DAMHDM greatly reduced protein adsorption and inhibited biofilm viability. Copyright 2018, Japanese Society for Dental Materials and Devices. All rights reserved.
SponsorsThis study was supported by Natural Science Foundation of China NSFC 81500879 (NZ), Beijing Municipal Administration of Hospitals' Youth Program QML20161501 (NZ), Beijing Municipal Science and Technology Commission Z151100003915137 (YB), Beijing Municipal Hospitals' Program ZYLX201703 (YB), NIH R01 DE17974 (HX) and a Seed Grant (HX) from the University of Maryland School of Dentistry.
Identifier to cite or link to this itemhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85061893126&doi=10.4012%2fdmj.2017-422&partnerID=40&md5=e42fbd8eb3a0017bcb591353d118d24c; http://hdl.handle.net/10713/9315