Periodontal, metabolic, and cardiovascular disease: Exploring the role of inflammation and mental health
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AbstractPrevious evidence connects periodontal disease, a modifiable condition affecting a majority of Americans, with metabolic and cardiovascular morbidity and mortality. This review focuses on the likely mediation of these associations by immune activation and their potential interactions with mental illness. Future longitudinal, and ideally interventional studies, should focus on reciprocal interactions and cascading effects, as well as points for effective preventative and therapeutic interventions across diagnostic domains to reduce morbidity, mortality and improve quality of life. Copyright 2018 Hina Makkar et al.
SponsorsThis work was supported by the Mid-Atlantic Nutrition Obesity Research Center Pilot NORC grant (Postolache, PI), a subaward of the parent grant P30 DK072488 (Mitchell, PI).
Identifier to cite or link to this itemhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85058419451&doi=10.1515%2fpteridines-2018-0013&partnerID=40&md5=9385fc71300d5955c9517d8687636968; http://hdl.handle.net/10713/9172