• Login
    View Item 
    •   UMB Digital Archive
    • School, Graduate
    • Theses and Dissertations All Schools
    • View Item
    •   UMB Digital Archive
    • School, Graduate
    • Theses and Dissertations All Schools
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of UMB Digital ArchiveCommunitiesPublication DateAuthorsTitlesSubjectsThis CollectionPublication DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    Statistics

    Display statistics

    Histomorphometric Analysis of Mouse Growth Plate during Maturation and Senescence.

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    Wilson_umaryland_0373N_11016.pdf
    Size:
    1.760Mb
    Format:
    PDF
    Download
    Author
    Wilson, Kimberly
    Advisor
    Enomoto-Iwamoto, Motomi
    Date
    2018
    Embargo until
    07/01/2019
    Type
    dissertation
    
    Metadata
    Show full item record
    Abstract
    The growth plate (GP) is cartilage tissue at both ends of long bones and plays an essential role for long bone formation and growth. GP changes in overall height, width, zone proportion, cell density and size during skeletal growth and becomes arrested upon skeletal maturation. There is limited information on GP microscopic changes. To establish GP histomorphometric parameters changes throughout skeletal maturation, the tibia of C57Bl/6J mice were evaluated from neonatal to young adult stages. GP histology in the proximal tibia was analyzed regarding total and zone height, width and area. The results showed unique GP changes in width, height and area during growth. The parameters also showed strong correlation with growth rate of the tibia. We studied GP proliferation activity and also found its correlation with tibia growth rate. The results of this study provide groundwork that will aid skeletal research on understanding of GP changes during bone growth.
    Description
    2018
    Medical and Research Technology
    University of Maryland, Baltimore
    M.S.
    Keyword
    histomorphometry
    Bone Development
    Growth Plate--anatomy & histology
    Mice
    Identifier to cite or link to this item
    http://hdl.handle.net/10713/8998
    Collections
    Theses and Dissertations School of Medicine
    Theses and Dissertations All Schools

    entitlement

     
    DSpace software (copyright © 2002 - 2023)  DuraSpace
    Quick Guide | Policies | Contact Us | UMB Health Sciences & Human Services Library
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.