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dc.contributor.authorCarbon, S.
dc.contributor.authorDouglass, E.
dc.contributor.authorDunn, N.
dc.date.accessioned2019-03-29T14:47:40Z
dc.date.available2019-03-29T14:47:40Z
dc.date.issued2019
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85059799086&doi=10.1093%2fnar%2fgky1055&partnerID=40&md5=a5267cde8da36cae99ab96fb258a8dcd
dc.identifier.urihttp://hdl.handle.net/10713/8737
dc.description.abstractThe Gene Ontology resource (GO; http://geneontology.org) provides structured, computable knowledge regarding the functions of genes and gene products. Founded in 1998, GO has become widely adopted in the life sciences, and its contents are under continual improvement, both in quantity and in quality. Here, we report the major developments of the GO resource during the past two years. Each monthly release of the GO resource is now packaged and given a unique identifier (DOI), enabling GO-based analyses on a specific release to be reproduced in the future. The molecular function ontology has been refactored to better represent the overall activities of gene products, with a focus on transcription regulator activities. Quality assurance efforts have been ramped up to address potentially out-of-date or inaccurate annotations. New evidence codes for high-Throughput experiments now enable users to filter out annotations obtained from these sources. GO-CAM, a new framework for representing gene function that is more expressive than standard GO annotations, has been released, and users can now explore the growing repository of these models. We also provide the 'GO ribbon' widget for visualizing GO annotations to a gene; the widget can be easily embedded in any web page. © The Author(s) 2018. Published by Oxford University Press on behalf of Nucleic Acids Research.en_US
dc.description.urihttps://dx.doi.org/10.1093/nar/gky1055en_US
dc.language.isoen_USen_US
dc.publisherOxford University Pressen_US
dc.relation.ispartofNucleic Acids Research
dc.subjectGene Ontology Consortiumen_US
dc.subject.meshBiological Ontologiesen_US
dc.subject.meshGene Ontologyen_US
dc.titleThe Gene Ontology Resource: 20 years and still GOing strongen_US
dc.typeArticleen_US
dc.identifier.doi10.1093/nar/gky1055
dc.identifier.pmid30395331


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