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dc.contributor.authorMcKinnon, L.R.
dc.contributor.authorAchilles, S.L.
dc.contributor.authorBradshaw, C.S.
dc.date.accessioned2019-03-29T14:47:38Z
dc.date.available2019-03-29T14:47:38Z
dc.date.issued2019
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85062412846&doi=10.1089%2faid.2018.0304&partnerID=40&md5=ef41b861ea1e9f02ef360c33971fb3e6
dc.identifier.urihttp://hdl.handle.net/10713/8707
dc.description.abstractBacterial vaginosis (BV) is a common yet poorly understood vaginal condition that has become a major focus of HIV transmission and immunology research. Varied terminologies are used by clinicians and researchers to describe microbial communities that reside in the female reproductive tract (FRT), which is driven, in part, by microbial genetic and metabolic complexity, evolving diagnostic and molecular techniques, and multidisciplinary perspectives of clinicians, epidemiologists, microbiologists, and immunologists who all appreciate the scientific importance of understanding mechanisms that underlie BV. This Perspectives article aims to clarify the varied terms used to describe the cervicovaginal microbiota and its "nonoptimal" state, under the overarching term of BV. The ultimate goal is to move toward language standardization in future literature that facilitates a better understanding of the impact of BV on FRT immunology and risk of sexually transmitted infections, including HIV. © Lyle R. McKinnon et al. 2019; Published by Mary Ann Liebert, Inc. 2019.en_US
dc.description.sponsorshipA.D.B. and L.R.M. are funded by the Canadian Institutes of Health Research (CIHR) grant TMI-138658. L.R.M. is supported by a CIHR New Investigator award and A.D.B. by the CIHR New Investigator in HIV award NIH-15404. R.K. is funded by CIHR grant PJT-156123. C.K. is funded by an Ontario HIV Treatment Network Applied HIV Chair award and operating grants and an HIV Team grant from CIHR. J.R. was supported by the National Institute for Allergy and Infectious Diseases of the National Institutes of Health under award number U19AI084044. G.T. is funded by the National Health and Medical Research Council of Australia Senior Research Fellowship GNT1117748. G.T. gratefully acknowledges the contribution of the Victorian Operational Infrastructure Support Program received by the Burnet Institute.en_US
dc.description.urihttps://dx.doi.org/10.1089/aid.2018.0304en_US
dc.language.isoen_USen_US
dc.publisherMary Ann Liebert Inc.en_US
dc.relation.ispartofAIDS Research and Human Retroviruses
dc.subjectbacterial vaginosisen_US
dc.subjectfemale reproductive tracten_US
dc.subjectgenital inflammationen_US
dc.subjectHIVen_US
dc.subjectHIV transmissionen_US
dc.subjectvaginal microbiotaen_US
dc.titleThe Evolving Facets of Bacterial Vaginosis: Implications for HIV Transmissionen_US
dc.typeReviewen_US
dc.identifier.doi10.1089/aid.2018.0304
dc.identifier.pmid30638028


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