Prevalence and incidence of genital warts and cervical Human Papillomavirus infections in Nigerian women 11 Medical and Health Sciences 1117 Public Health and Health Services
JournalBMC Infectious Diseases
PublisherBioMed Central Ltd.
MetadataShow full item record
AbstractBackground: Genital warts are important causes of morbidity and their prevalence and incidence can be used to evaluate the impact of HPV vaccination in a population. Methods: We enrolled 1020 women in a prospective cohort study in Nigeria and followed them for a mean (SD) of 9 (4) months. Nurses conducted pelvic examinations and collected ectocervical samples for HPV testing. We used exact logistic regression models to identify risk factors for genital warts. Results: The mean age of study participants was 38 years, 56% (535/962) were HIV-negative and 44% (427/962) were HIV-positive. Prevalence of genital warts at enrolment was 1% (4/535) among HIV-negative women, and 5% (23/427) among HIV-positive women. Of 614 women (307 HIV negative and 307 HIV positive women) for whom we could compute genital wart incidence, it was 515 (95% CI:13-2872) per 100,000 person-years in HIV-negative and 1370 (95% CI:283-4033) per 100,000 person-years in HIV-positive women. HIV was associated with higher risk of prevalent genital warts (OR:7.14, 95% CI:2.41-28.7, p < 0.001) while higher number of sex partners in the past year was associated with increased risk of incident genital warts (OR:2.86, 95% CI:1.04-6.47. p = 0.04). HPV11 was the only HPV associated with prevalent genital warts in this population (OR:8.21, 95% CI:2.47-27.3, p = 0.001). Conclusion: Genital warts are common in Nigeria and our results provide important parameters for monitoring the impact of future HPV vaccination programs in the country. HIV infection and number of sexual partners in past year were important risk factors for prevalent and incident genital warts respectively. © 2019 The Author(s).
Identifier to cite or link to this itemhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85059748060&doi=10.1186%2fs12879-018-3582-y&partnerID=40&md5=fd3a8a7893e5a15960ebc12a9861b883; http://hdl.handle.net/10713/8646
- Spectrum of genital human papillomavirus infection in a female adolescent population.
- Authors: Jamison JH, Kaplan DW, Hamman R, Eagar R, Beach R, Douglas JM Jr
- Issue date: 1995 Jul-Aug
- Prevalence, incidence and correlates of low risk HPV infection and anogenital warts in a cohort of women living with HIV in Burkina Faso and South Africa.
- Authors: Chikandiwa A, Kelly H, Sawadogo B, Ngou J, Pisa PT, Gibson L, Didelot MN, Meda N, Weiss HA, Segondy M, Mayaud P, Delany-Moretlwe S, HARP Study Group.
- Issue date: 2018
- Genital warts and infection with human immunodeficiency virus in high-risk women in Burkina Faso: a longitudinal study.
- Authors: Low AJ, Clayton T, Konate I, Nagot N, Ouedraogo A, Huet C, Didelot-Rousseau MN, Segondy M, Van de Perre P, Mayaud P, Yérélon Cohort Study Group.
- Issue date: 2011 Jan 20
- Prevalence and correlates of cervical HPV infection in a clinic-based sample of HIV-positive Hispanic women.
- Authors: Ortiz AP, Tamayo V, Scorsone A, Soto-Salgado M, Febo I, Piovanetti P, Venegas-Ríos HL, Yamamura Y, Zorrilla C
- Issue date: 2017 Dec
- High prevalence of genital HPV infection among long-term monogamous partners of women with cervical dysplasia or genital warts-Another reason for HPV vaccination of boys.
- Authors: Rob F, Tachezy R, Pichlík T, Rob L, Kružicová Z, Hamšíková E, Šmahelová J, Hercogová J
- Issue date: 2017 Jan