Browsing UMB Open Access Articles by Title "Radiation Myelopathy of the Cervical Spine in the Setting of Neuromyelitis Optica Spectrum Disorder After Low-Dose Radiation Therapy for Non-Hodgkin Lymphoma of the Cervical Lymph Nodes"
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Radiation Myelopathy of the Cervical Spine in the Setting of Neuromyelitis Optica Spectrum Disorder After Low-Dose Radiation Therapy for Non-Hodgkin Lymphoma of the Cervical Lymph NodesThe spinal cord, as a late-responding tissue, is a relatively radiosensitive structure. Radiation myelopathy (RM) is a very rare but potentially catastrophic complication. RM is defined as damage of the white matter of the spinal cord after exposure to ionizing radiation. Glial and vascular damage from radiation likely both contribute to this pathophysiology.1,2 It is often a diagnosis of exclusion based on a history of prior radiation of sufficient dose to cause cord injury, the region of irradiated cord being superior to the region of symptoms, presence of a latency period from completion of treatment, and a lack of explanatory disease progression.
