• Intracranial Arterial Calcification and Intracranial Atherosclerosis: Close but Different.

      Du, Heng; Li, Jia; Yang, Wenjie; Bos, Daniel; Zheng, Lu; Wong, Lawrence Ka Sing; Leung, Thomas W; Chen, Xiangyan (Frontiers Media S.A., 2022-02-08)
      Among 69 patients with stroke, IAC was identified in 35% of (161/483) artery segments, of which 61.5% were predominantly intimal calcification and 38.5% were predominantly medial calcification. About 79.8% of intimal calcifications and 64.5% of medial calcifications co-existed with atherosclerotic plaques. Intimal calcification was associated with luminal stenosis (p = 0.003) caused by atherosclerotic lesions. Compared with the medial IAC, intimal IAC was more often accompanied by eccentric plaques (p = 0.02), larger plaque burden (p = 0.001), and IPH (p = 0.001).