Clinical and Translational Research at UMB: Recent submissions
Now showing items 1-20 of 155
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ICTR at Medical Grand Rounds: Utilization and Effectiveness of Using a Patient Portal for Health Research RecruitmentCarrie Dykes explores the utilization of MyChart, a patient portal, for health research recruitment at the University of Rochester Clinical and Translational Science Institute. MyChart facilitated efficient communication, engagement, and enrollment of participants in various studies, with the presentation highlighting lessons learned and positive feedback from study teams.
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ICTR at Medical Grand Rounds: Discovering New Medicines in AcademiaSlusher discusses the Johns Hopkins Drug Discovery Program, which commenced in 2010 and focuses on small molecule drug discovery with collaborative efforts in academia and community services.
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ICTR at Medical Grand Rounds: Diagnosis of Viral Community-acquired PneumoniaBaghdadi discusses viral community-acquired pneumonia and his research on designing a diagnostic pathway to improve antibiotic use for community-acquired pneumonia, emphasizing the importance of diagnostic stewardship.
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ICTR at Medical Grand Rounds: Innovative Strategies for Navigating ML/AI Ready Digitized Medical Health DataSchriml discusses a data portal project to connect diverse research projects, establishing interoperability without altering existing data structures. Using a unified ontology, the project mapped and linked varied data sets, facilitating seamless data integration.
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ICTR at Medical Grand Rounds: Cumulative Risk Factor Exposure and Cardiovascular DiseaseDomanski discusses a paper on the Association of Incident Cardiovascular Disease with Time Course and Cumulative Exposure to Multiple Risk Factors. Utilizing data from the Cardia study, a long-term study with 35 years of follow-up, to understand the impact of multiple risk factors on cardiovascular disease, the analysis involves a knowledge-guided machine learning procedure, focusing on influential risk predictors and dealing with highly correlated predictors.
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ICTR at Medical Grand Rounds: Use of Visual Deprivation to Promote the Recovery from Severe Amblyopia: Translation from Animal Models to HumansQuinlan discusses her work on translating foundational research from animal models to humans. She explores the critical period for plasticity, the impact of synaptic plasticity decline with age, and her experiments using visual deprivation to unmask plasticity in the adult cortex.
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ICTR at Medical Grand Rounds: Harnessing our Common African Genome to Improve Health GloballyWonkam discusses the imperative need to research African genomic variation.
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ICTR at Medical Grand Rounds: Moving Fruits, Vegetables, Nuts, and Beans through the Translational Research PathwayMiller discusses the impact of diet modification on blood pressure, and the impact of providing health foods and advice on health food intake.
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ICTR Enrichment Series: Opportunities for Healthcare Research Using Administrative Data: An Introduction to the IQVIATM Health Plans Claims DatadosRein and Onukwugha overview IQVIA Health Plan Claims Data, ICTR support for projects using IQVIA data, steps to obtain ICTR support, and discuss an example project.
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ICTR Enrichment Series: Community Based Participatory Research: Challenges and RewardsDrs. Rosenthal and Doherty discuss Community Based Participatory Research (CBPR), a collaborative approach to research that involves all stakeholders throughout the research process.
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ICTR Enrichment Series: Innovative Ways Using Social Media Platforms for Research Participant Recruitment and ParticipationDr. Rachel Blankstein Breman discusses using social media for recruitment research and Dr. Jaih Craddock discusses text-based recruitment.
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ICTR Enrichment Series: Patient-Centered Research: Increase Access and Impact of Clinical Research and Trials to Reduce Health DisparitiesDiscussion Synopsis: Jain talks about his experience with several research programs, small and large, that are utilizing these innovative, evidence-based digital tools and resources to conduct patient powered/patient centered precision research. These tools are scientifically proven and have been shown to reduce barriers to clinical research. Jain also talks about how ICTR can build capacity for successful pragmatic clinical trials, investigator-initiated studies, and industry clinical trials, through digital tools, training, and processes. Jain highlights a few research programs such as the NIH All of Us, a large longitudinal study, that has successfully achieved high, multi-year RETENTION through community engagement.
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ICTR Enrichment Series: Creating a centralized social media service to raise awareness about research opportunities and to grow our volunteer registry at the University of MichiganDiscussion synopsis: While exploring ways to assist study teams expand recruitment efforts into traditionally underserved and underrepresented communities, the Participant Recruitment Team began to research paid, targeted social media advertising. This merging recruitment strategy seemed like a viable option, but we found that most study teams didn’t feel they had the expertise or the bandwidth to explore this method. A survey of researchers on campus found that over 70% said they would utilize social media as a recruitment strategy if someone else created the campaign and monitored the analytics for them. Connally discusses how a centralized service was created to assist with social media advertising at the University of Michigan.
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ICTR Enrichment Series: NHLBI Catalyze Program: Providing Bridge from Basic to Clinical ResearchThis Enrichment seminar covers the discovery of novel kinase inhibitors that mitigate pathological airway remodeling associated with asthma. Dr. Shapiro discusses how ICTR resources helped generate preliminary data and NIH funding through the R61/R33 Catalyze program at the National Heart, Lung, and Blood Institute. The talk also covers the goals of the Catalyze program and its role in promoting the development of new therapies and entrepreneurial activities. Dr. Shapiro’ concludes with ICTR pilot grant and micro-grant opportunities as well as ICTR cores of services available to researchers.
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ICTR Enrichment Series: Navigating the NIH Data Management and Sharing Policy: Tools, Strategies, and Best PracticesThe Data Services Librarians from the Health Sciences and Human Services Library (HSHSL) provide an overview of the new NIH Data Management and Sharing Policy (DMSP) and resources available to help comply with requirements. The seminar covers the free online application DMPTool, strategies for choosing a data repository, and insights into data sharing best practices.
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ICTR Enrichment Series: Research with Impact! Dissemination and Implementation(D&I) Science to Inform Clinical Care and Prevention Strategies: from Data to ActionIn this talk, Dr. Shaya presents cases of D&I in clinical and translational research, in the context of drug prescribing, and substance use prevention. She showcases success stories and dissemination products. She presents translational science methods, including rigorous needs assessment, data sourcing and analysis, dissemination of findings and as well as strategies for supporting successful implementation in clinical and public health practice.
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ICTR Enrichment Series: Overview of Drug Development and UMB ResourcesIn this talk, Dr. Quraishi demystifies the process of drug development given that it takes seven to ten years, costs millions of dollars, there is no return on investment until the drug is approved, and failure rates are very high. Additionally, there is a complex regulatory pathway and a lot of competition. Dr. Quraishi discusses how all this is managed. She spends the second part of the talk discussing services and support the New Ventures group offers and is developing for those interested in the commercialization of their discovery.
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ICTR Enrichment Series: Towards Building a Clinically-Inspired Ultrasound Innovation Hub: Design, Development and Clinical Validation of Ultrasound Probes for Imaging, Therapeutics, Sensing and Other ApplicationsUltrasound is a relatively established modality with a number of exciting, yet not fully explored applications, ranging from imaging and image-guided navigation to tumor ablation, neuromodulation, piezoelectric surgery, and drug delivery. In this talk, Dr. Manbachi discusses some of his ongoing projects aiming to address low-frequency neuromodulation, minimally invasive ablation of neuro-oncology and implantable sensors for spinal cord blood flow measurements.
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ICTR Enrichment Series: "Clinical Utility of Testing Symptomatic Women for Both Sexually Transmitted Infections (STIs) & Vaginitis” and “Cervical Cancer Screening in the Era of the Covid-19 PandemicTwo presentations by BD Innovation Center staff. The BD Innovation Center recently opened a state-of-the-art facility at the University of Maryland BioPark that will give students and researchers access to new laboratory space and advanced diagnostic tools. The center’s goal is to help streamline clinical laboratory workflows and improve patient care by expanding basic diagnostic knowledge, developing new diagnostic capabilities, and shaping the future of diagnostics by allowing students and researchers to provide real-world feedback on early diagnostic concepts.
