Center for Celiac Research

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Founded by Dr. Alessio Fasano at the University of Maryland School of Medicine in Baltimore in 1996, the Center for Celiac Research is dedicated to improving the quality of life for patients with celiac disease, while learning the cause of the disease and finding a cure. The Center has since relocated to Boston to become part of Massachusetts General Hospital for Children.

Recent Submissions

Fact Sheet on Irritable Bowel Syndrome and Celiac Disease

University of Maryland, Baltimore. School of Medicine. Center for Celiac Disease
Abstract: Celiac Disease in Children With Type I Diabetes in Southern California

Pietzak, Michelle; Wolfe, Adam; Rongey, Christine; Kaufman, Francine Ratner; Fisher, Lynda; Devoe, Debra; Pisit, Duke; Berti, Irene, M.D.; Gerarduzzi, Tania; Thorpe, Mary; et al. (2002)
Intestinal Permeability, Zonulin and Liver Cirrhosis

Sapone, Anna; de Magistris, Laura; Fiandra, Raffaele; Federico, Alessandro; D'Auria, Mauro; Blanco, Camillo Del Cecchio; Fasano, Alessio; Lo Guercio, Carmelina (2006)
Seric Zonulin, a Modulator of Intestinal Tight Junctions Permeability, is Increased in Different Autoimmune Disorders

Clemente, Maria Grazia; Musu, Maria Paola; Counts, Debra; De Virgiliis, Stefano; Fasano, Alessio (2002)
The Gut Protein Zonulin is Increased in Patients with Type 1 Diabetes and Their First Degree Relatives

Counts, Debra; Clemente, Maria Grazia; Fasano, Alessio (2002)
Is there a primary increase in epithelial cell permeability in coeliac disease?

Fasano, Alessio (2002)
Celiac Disease

Fasano, Alessio (2006)
Abstract: Human tissue transglutaminase (htTG): a revision of an old blood donor screening!

Neri, Elena; Horvath, Karoly, M.D.; Not, Tarcisio; Rabsztyn, Anna, M.D.; Berti, Irene, M.D.; Drago, Sandro; Ventura, A.; Di Pierro, Mariarosaria; Gerarduzzi, Tania; Kryszak, Deborah; et al. (2002)
Gliadin Induces Zonulin Release, Occludin Down-Regulation, and Tight Junctions Disassembly in a Rat Animal Model

Drago, Sandro; Di Pierro, Mariarosaria; Margaretten, Klara; Thakar, Manjusha; Fasano, Alessio (2001)
Abstract: Gliadin Induces Occludin Down-Regulation and Tight Junctions Disassembly in Human Intestine

Drago, Sandro; El Asmar, Ramzi; Di Pierro, Mariarosaria; Gianbelluca, D.; Iacono, Giuseppe; Catassi, C. (Carlo) (2002)
Seric Zonulin, A Modulator of Tight Junctions Permeability, Is Increased in Different Autoimmune Disorders

Clemente, Maria Grazia; Musu, Maria Paola; Counts, Debra; De Virgiliis, Stefano; Fasano, Alessio (2002)
New insights on celiac disease pathogenesis: gliadin effects on Zonulin release and intestinal permeability

Drago, Sandro; Di Pierro, Mariarosaria; Margaretten, Klara; Thakar, Manjusha; Fasano, Alessio (2002)
Abstract: PBMC From a Subpopulation of Celiac Patients Respond to Gliadin With Interleukin-8 Production That is CXCR3-Dependent

Khandelwal, Sunaina; Lammers, Karen M.; Kryszak, Deborah; Casolaro, Vincenzo; Fasano, Alessio (2009)
Abstract: Gluten Sensitivity is Associated to Activation of The Innate But Not Adaptive Immune Response to Gluten Exposure

Sapone, Anna; Carteni, Maria; Tolone, Carlo; Papparella, Alfonso; Stefanile, Rosita; Mazzarella, Giuseppe; Russo, Maria Itria; Esposito, Pasquale; Lammers, Karen M.; Casolaro, Vincenzo; et al. (2009)
The Natural History of Undiagnosed Celiac Disease: A Retrospective Study

Sturgeon, Craig; Bhatti, Bushra; Kryszak, Deborah; Catassi, C. (Carlo); Helzlsouer, Kathy; Clipp, Sandra L.; Fasano, Alessio (2009)
Abstract: Probiotic Lactobacillus GG Secretes Small Peptides That Inhibit the Growth of Antibiotic-Resistant Bacteria

Lu, Ruiliang; Fasano, Alessio (2009)
The Gluten Link: The Connection between Schizophrenia and Celiac Disease

Bhatti, Bushra; Sturgeon, Craig; Kryszak, Deborah; Gregory, Patricia; Eaton, William W.; Cascella, Nicola; Fasano, Alessio (2009)
Activation of Innate and not Adaptive Immune system in Gluten Sensitivity

Sapone, Anna; de Magistris, Laura; Cammarota, Marcella; Giuliano, Maria Teresa; De Rosa, Mario; Carteni, Maria; Tolone, Carlo; Papparella, Alfonso; Stefanile, Rosita; Mazzarella, Giuseppe; et al. (2009)
Intestinal Zot/Zonulin Receptor Is Up-Regulated In Active Celiac Disease and Co-Localizes With Proteinase-Activated Receptor (PAR)-2

Clemente, Maria Grazia; De Virgiliis, Stefano; Musu, Maria Paola; Usai, Paolo; Porqueddu, Patrizia; Cicotto, Lucia; Massidda, Carlo; Fasano, Alessio (2011)
Salmonella typhi induces increased mucosal permeability and elicits a strong pro-inflammatory response ameliorated by vaccine candidates in vitro

Fiorentino, Maria R., Ph.D.; Test, Test2; Lammers, Karen M.; Dyson, Tristan; Vogel, Stefanie N.; Fasano, Alessio (2010)

Center for Celiac Research

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Recent Submissions

Fact Sheet on Irritable Bowel Syndrome and Celiac Disease

Abstract: Celiac Disease in Children With Type I Diabetes in Southern California

Intestinal Permeability, Zonulin and Liver Cirrhosis

Seric Zonulin, a Modulator of Intestinal Tight Junctions Permeability, is Increased in Different Autoimmune Disorders

The Gut Protein Zonulin is Increased in Patients with Type 1 Diabetes and Their First Degree Relatives

Is there a primary increase in epithelial cell permeability in coeliac disease?

Celiac Disease

Abstract: Human tissue transglutaminase (htTG): a revision of an old blood donor screening!

Gliadin Induces Zonulin Release, Occludin Down-Regulation, and Tight Junctions Disassembly in a Rat Animal Model

Abstract: Gliadin Induces Occludin Down-Regulation and Tight Junctions Disassembly in Human Intestine

Seric Zonulin, A Modulator of Tight Junctions Permeability, Is Increased in Different Autoimmune Disorders

New insights on celiac disease pathogenesis: gliadin effects on Zonulin release and intestinal permeability

Abstract: PBMC From a Subpopulation of Celiac Patients Respond to Gliadin With Interleukin-8 Production That is CXCR3-Dependent

Abstract: Gluten Sensitivity is Associated to Activation of The Innate But Not Adaptive Immune Response to Gluten Exposure

The Natural History of Undiagnosed Celiac Disease: A Retrospective Study

Abstract: Probiotic Lactobacillus GG Secretes Small Peptides That Inhibit the Growth of Antibiotic-Resistant Bacteria

The Gluten Link: The Connection between Schizophrenia and Celiac Disease

Activation of Innate and not Adaptive Immune system in Gluten Sensitivity

Intestinal Zot/Zonulin Receptor Is Up-Regulated In Active Celiac Disease and Co-Localizes With Proteinase-Activated Receptor (PAR)-2

Salmonella typhi induces increased mucosal permeability and elicits a strong pro-inflammatory response ameliorated by vaccine candidates in vitro