Abstract
The importance of the microbiota-gut-brain axis has been of major interest in mental health research in recent years. In addition, research endeavors have expanded to also include the role of the oral microbiota in mental health. The articles published as part of this Frontiers Research Topic provide insight into the bidirectional connection between periodontal and mental health and the reciprocal interaction between the oral microbiota and central nervous system (CNS). This bidirectional axis provides potential targetable molecular, cellular and behavioral interventions that might contribute to the prevention of precipitation, reactivation, exacerbation, and progression of mental health disorders, to be investigated in controlled experimental and clinical models.Keyword
anxietydepression
inflammation
microbiome
oral health
oral microbiota
oral-brain axis
periodontitis
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http://hdl.handle.net/10713/20052ae974a485f413a2113503eed53cd6c53
10.3389/fpsyt.2022.1048179
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