Editorial: Quantifying and controlling the nano-architecture of neuronal synapses.

Abstract

About 2 years ago when the journal gave us the opportunity to launch this Research Topic, the three of us were excited by the rapid growth of cutting-edge imaging approaches now illuminating the architecture and molecular organization of synapses. Since its launch, we received enthusiastic responses from many authors and in the end, we published 15 articles in this volume.

These articles, including original research, reviews, and opinion, present a snapshot of several key active areas of ongoing work. They fall roughly into three areas: technical advances in single-molecule imaging and analysis, dynamics of molecular organization within the synapse, and advances in electron microscopy that are propelling new insights.