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    Core-shell nanostructures for improving dental restorative materials: A scoping review of composition, methods, and outcome

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    Author
    Mokeem, Lamia Sami
    Garcia, Isadora Martini
    Shahkarami, Yasmin
    Blum, Lauren
    Balhaddad, Abdulrahman A.
    Collares, Fabrício Mezzomo
    Williams, Mary Ann
    Weir, Michael D.
    Melo, Mary Anne S.
    Date
    2023-01-01
    Journal
    Smart Materials in Medicine
    Type
    Article
    
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    See at
    https://doi.org/10.1016/j.smaim.2022.08.002
    Abstract
    Dental resin adhesives and composites are the most prevailing dental restorative materials used to treat cavitated tooth decay. These materials are challenged inside the mouth by bacterial acid attack, lack of bioactivity, and the scarcity of alternatives maintaining the mechanical properties over the lifetime service of these materials. Core-shell nanostructures are composed of various materials surrounded by a protective shell. They are acquiring considerable attention as innovative multipurpose carriers that show great potential in restorative dentistry. Herein, we systematically reviewed the recent studies on core-shell nanostructures incorporated into dental resin-based materials, their intended properties, synthesis methods, and assessment tests employed. This study used scoping review method, following Arksey and O'Malley's five stages framework using PubMed and Scopus (Elsevier) databases. From 149 initially identified manuscripts, 20 studies were eligible for full-text screening, and 15 were included for data extraction. The majority of included studies have used resin composite as parental material. Silica oxide was the most prevailing shell incorporated into dental resins. Almost all core-shell nanostructures were added to improve the material's strength and impart antibacterial properties. Designing strategies and drug release behaviors were discussed. In the end, current challenges and prospects in this promising field were highlighted.
    Keyword
    Dental caries
    Dental materials
    Drug delivery
    Nanoparticles
    Nanotechnology
    Identifier to cite or link to this item
    http://hdl.handle.net/10713/19812
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.smaim.2022.08.002
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