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dc.contributor.authorNieman, Gary
dc.contributor.authorKollisch-Singule, Michaela
dc.contributor.authorRamcharran, Harry
dc.contributor.authorSatalin, Joshua
dc.contributor.authorBlair, Sarah
dc.contributor.authorGatto, Louis A
dc.contributor.authorAndrews, Penny
dc.contributor.authorGhosh, Auyon
dc.contributor.authorKaczka, David W
dc.contributor.authorGaver, Donald
dc.contributor.authorBates, Jason
dc.contributor.authorHabashi, Nader M
dc.date.accessioned2022-08-10T12:37:54Z
dc.date.available2022-08-10T12:37:54Z
dc.date.issued2022-08-07
dc.identifier.urihttp://hdl.handle.net/10713/19546
dc.description.abstractA hallmark of ARDS is progressive shrinking of the 'baby lung,' now referred to as the ventilator-induced lung injury (VILI) 'vortex.' Reducing the risk of the VILI vortex is the goal of current ventilation strategies; unfortunately, this goal has not been achieved nor has mortality been reduced. However, the temporal aspects of a mechanical breath have not been considered. A brief expiration prevents alveolar collapse, and an extended inspiration can recruit the atelectatic lung over hours. Time-controlled adaptive ventilation (TCAV) is a novel ventilator approach to achieve these goals, since it considers many of the temporal aspects of dynamic lung mechanics.en_US
dc.description.urihttps://doi.org/10.1186/s13054-022-04105-xen_US
dc.language.isoenen_US
dc.publisherSpringer Natureen_US
dc.relation.ispartofCritical Care (London, England)en_US
dc.rights© 2022. The Author(s).en_US
dc.subjectAcute respiratory distress syndrome (ARDS)en_US
dc.subjectProtective mechanical ventilationen_US
dc.subjectVentilator-induced lung injury (VILI)en_US
dc.titleUnshrinking the baby lung to calm the VILI vortex.en_US
dc.typeArticleen_US
dc.identifier.doi10.1186/s13054-022-04105-x
dc.identifier.pmid35934707
dc.source.journaltitleCritical care (London, England)
dc.source.volume26
dc.source.issue1
dc.source.beginpage242
dc.source.endpage
dc.source.countryUnited States
dc.source.countryEngland


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