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    Unshrinking the baby lung to calm the VILI vortex.

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    Author
    Nieman, Gary
    Kollisch-Singule, Michaela
    Ramcharran, Harry
    Satalin, Joshua
    Blair, Sarah
    Gatto, Louis A
    Andrews, Penny
    Ghosh, Auyon
    Kaczka, David W
    Gaver, Donald
    Bates, Jason
    Habashi, Nader M
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    Date
    2022-08-07
    Journal
    Critical Care (London, England)
    Publisher
    Springer Nature
    Type
    Article
    
    Metadata
    Show full item record
    See at
    https://doi.org/10.1186/s13054-022-04105-x
    Abstract
    A hallmark of ARDS is progressive shrinking of the 'baby lung,' now referred to as the ventilator-induced lung injury (VILI) 'vortex.' Reducing the risk of the VILI vortex is the goal of current ventilation strategies; unfortunately, this goal has not been achieved nor has mortality been reduced. However, the temporal aspects of a mechanical breath have not been considered. A brief expiration prevents alveolar collapse, and an extended inspiration can recruit the atelectatic lung over hours. Time-controlled adaptive ventilation (TCAV) is a novel ventilator approach to achieve these goals, since it considers many of the temporal aspects of dynamic lung mechanics.
    Rights/Terms
    © 2022. The Author(s).
    Keyword
    Acute respiratory distress syndrome (ARDS)
    Protective mechanical ventilation
    Ventilator-induced lung injury (VILI)
    Identifier to cite or link to this item
    http://hdl.handle.net/10713/19546
    ae974a485f413a2113503eed53cd6c53
    10.1186/s13054-022-04105-x
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