Author
Nieman, GaryKollisch-Singule, Michaela
Ramcharran, Harry
Satalin, Joshua
Blair, Sarah
Gatto, Louis A
Andrews, Penny
Ghosh, Auyon
Kaczka, David W
Gaver, Donald
Bates, Jason
Habashi, Nader M
Date
2022-08-07Journal
Critical Care (London, England)Publisher
Springer NatureType
Article
Metadata
Show full item recordAbstract
A hallmark of ARDS is progressive shrinking of the 'baby lung,' now referred to as the ventilator-induced lung injury (VILI) 'vortex.' Reducing the risk of the VILI vortex is the goal of current ventilation strategies; unfortunately, this goal has not been achieved nor has mortality been reduced. However, the temporal aspects of a mechanical breath have not been considered. A brief expiration prevents alveolar collapse, and an extended inspiration can recruit the atelectatic lung over hours. Time-controlled adaptive ventilation (TCAV) is a novel ventilator approach to achieve these goals, since it considers many of the temporal aspects of dynamic lung mechanics.Rights/Terms
© 2022. The Author(s).Keyword
Acute respiratory distress syndrome (ARDS)Protective mechanical ventilation
Ventilator-induced lung injury (VILI)
Identifier to cite or link to this item
http://hdl.handle.net/10713/19546ae974a485f413a2113503eed53cd6c53
10.1186/s13054-022-04105-x
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