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dc.contributor.authorTippabhatla, Abhishek
dc.contributor.authorAtalay, Rediet T
dc.contributor.authorGyftopoulos, Alex
dc.contributor.authorAyele, Girma M
dc.contributor.authorMichael, Miriam B
dc.date.accessioned2022-08-01T12:53:07Z
dc.date.available2022-08-01T12:53:07Z
dc.date.issued2022-06-26
dc.identifier.urihttp://hdl.handle.net/10713/19484
dc.description.abstractDiffuse large B-cell lymphoma (DLBCL) is the most common non-Hodgkin's lymphoma (NHL) and accounts for approximately 25% of all NHLs in developed countries. The patients usually present with constitutional symptoms and rapidly enlarging lymphadenopathy and symptomatic mass typically located in the neck or abdomen, along with an aggressive disease course. Most of the patients present with advanced disease with 60% presenting with stage 3 or 4, and those who present with extranodal involvement are usually seen at an earlier stage. Different conditions are associated with non-Hodgkin's lymphoma ranging from hereditary immunodeficiency disorders, autoimmune disorders, infections such as HIV, Epstein-Barr virus (EBV), hepatitis C virus (HCV), Helicobacter pylori, and drugs such as immunosuppressants and chemotherapeutic agents. Epstein-Barr virus (EBV) is the main etiology of DLBCLs with an identified cause and it accounts for 10% of all DLBCLs.  We report a case of a 51-year-old woman who came with a non-traumatic left femur fracture and was subsequently found to have EBV-positive DLBCL. Lymphoma commonly presents as a lymph node swelling and it's uncommon to present as primary bone disease.en_US
dc.description.urihttps://doi.org/10.7759/cureus.26340en_US
dc.language.isoenen_US
dc.publisherCureus, Inc.en_US
dc.relation.ispartofCureusen_US
dc.rightsCopyright © 2022, Tippabhatla et al.en_US
dc.subjectbone lymphomaen_US
dc.subjectbone tumoren_US
dc.subjectebv-positiveen_US
dc.subjectpathologic fractureen_US
dc.subjectprimary bone tumoren_US
dc.titleEpstein-Barr Virus-Positive Not Otherwise Specified (EBV+ NOS) Lymphoma Presentation of Primary Bone Tumor Underlying a Pathological Fracture.en_US
dc.typeArticleen_US
dc.identifier.doi10.7759/cureus.26340
dc.identifier.pmid35903563
dc.source.journaltitleCureus
dc.source.volume14
dc.source.issue6
dc.source.beginpagee26340
dc.source.endpage
dc.source.countryUnited States


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