• Login
    View Item 
    •   UMB Digital Archive
    • UMB Open Access Articles
    • UMB Open Access Articles
    • View Item
    •   UMB Digital Archive
    • UMB Open Access Articles
    • UMB Open Access Articles
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of UMB Digital ArchiveCommunitiesPublication DateAuthorsTitlesSubjectsThis CollectionPublication DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    Statistics

    Display statistics

    Finding acute coronary syndrome with serial troponin testing for rapid assessment of cardiac ischemic symptoms (FAST-TRAC): a study protocol.

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Author
    Peacock, W Frank
    Maisel, Alan S
    Mueller, Christian
    Anker, Stefan D
    Apple, Fred S
    Christenson, Robert H
    Collinson, Paul
    Daniels, Lori B
    Diercks, Deborah B
    Somma, Salvatore Di
    Filippatos, Gerasimos
    Headden, Gary
    Hiestand, Brian
    Hollander, Judd E
    Kaski, Juan C
    Kosowsky, Joshua M
    Nagurney, John T
    Nowak, Richard M
    Schreiber, Donald
    Vilke, Gary M
    Wayne, Marvin A
    Than, Martin
    Show allShow less

    Date
    2022-06-30
    Journal
    Clinical and Experimental Emergency Medicine
    Publisher
    Korean Society of Emergency Medicine
    Type
    Article
    
    Metadata
    Show full item record
    See at
    https://doi.org/10.15441/ceem.21.154
    Abstract
    Objective: To determine the utility of a highly sensitive troponin assay when utilized in the emergency department. Methods: The FAST-TRAC study prospectively enrolled >1,500 emergency department patients with suspected acute coronary syndrome within 6 hours of symptom onset and 2 hours of emergency department presentation. It has several unique features that are not found in the majority of studies evaluating troponin. These include a very early presenting population in whom prospective data collection of risk score parameters and the physician's clinical impression of the probability of acute coronary syndrome before any troponin data were available. Furthermore, two gold standard diagnostic definitions were determined by a pair of cardiologists reviewing two separate data sets; one that included all local troponin testing results and a second that excluded troponin testing so that diagnosis was based solely on clinical grounds. By this method, a statistically valid head-to-head comparison of contemporary and high sensitivity troponin testing is obtainable. Finally, because of a significant delay in sample processing, a unique ability to define the molecular stability of various troponin assays is possible. Trial registration: ClinicalTrials.gov Identifier NCT00880802.
    Keyword
    Acute coronary syndrome
    Coronary artery disease
    Emergency medicine
    Myocardial infarction
    Troponin
    Identifier to cite or link to this item
    http://hdl.handle.net/10713/19474
    ae974a485f413a2113503eed53cd6c53
    10.15441/ceem.21.154
    Scopus Count
    Collections
    UMB Open Access Articles

    entitlement

    Related articles

    • A Randomized Trial of a 1-Hour Troponin T Protocol in Suspected Acute Coronary Syndromes: The Rapid Assessment of Possible Acute Coronary Syndrome in the Emergency Department With High-Sensitivity Troponin T Study (RAPID-TnT).
    • Authors: Chew DP, Lambrakis K, Blyth A, Seshadri A, Edmonds MJR, Briffa T, Cullen LA, Quinn S, Karnon J, Chuang A, Nelson AJ, Wright D, Horsfall M, Morton E, French JK, Papendick C
    • Issue date: 2019 Nov 5
    • High-sensitivity troponin assays for early rule-out of acute myocardial infarction in people with acute chest pain: a systematic review and economic evaluation.
    • Authors: Westwood M, Ramaekers B, Grimm S, Worthy G, Fayter D, Armstrong N, Buksnys T, Ross J, Joore M, Kleijnen J
    • Issue date: 2021 May
    • Diagnostic accuracy of contemporary and high-sensitivity cardiac troponin assays used in serial testing, versus single-sample testing as a comparator, to triage patients suspected of acute non-ST-segment elevation myocardial infarction: a systematic review protocol.
    • Authors: Zhelev Z, Ohtake H, Iwata M, Terasawa T, Rogers M, Peters JL, Hyde C
    • Issue date: 2019 Mar 30
    • Diagnostic and prognostic utility of early measurement with high-sensitivity troponin T assay in patients presenting with chest pain.
    • Authors: Aldous SJ, Richards M, Cullen L, Troughton R, Than M
    • Issue date: 2012 Mar 20
    • Ultra-Sensitive Copeptin and Cardiac Troponin in Diagnosing Non-ST-Segment Elevation Acute Coronary Syndromes--The COPACS Study.
    • Authors: Ricci F, Di Scala R, Massacesi C, Di Nicola M, Cremonese G, De Pace D, Rossi S, Griffo I, Cataldo I, Martinotti S, Rotondo D, Jaffe AS, Zimarino M, De Caterina R
    • Issue date: 2016 Jan
    DSpace software (copyright © 2002 - 2022)  DuraSpace
    Quick Guide | Policies | Contact Us | UMB Health Sciences & Human Services Library
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.