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dc.contributor.authorCanakis, Andrew
dc.contributor.authorLee, Linda S
dc.date.accessioned2022-06-22T13:42:54Z
dc.date.available2022-06-22T13:42:54Z
dc.date.issued2022-05
dc.identifier.urihttp://hdl.handle.net/10713/19230
dc.description.abstractGastroenteropancreatic neuroendocrine neoplasms are a heterogenous group of rare neoplasms that are increasingly being discovered, often incidentally, throughout the gastrointestinal tract with varying degrees of activity and malignant potential. Confusing nomenclature has added to the complexity of managing these lesions. The term carcinoid tumor and embryonic classification have been replaced with gastroenteropancreatic neuroendocrine neoplasm, which includes gastrointestinal neuroendocrine and pancreatic neuroendocrine neoplasms. A comprehensive multidisciplinary approach is important for clinicians to diagnose, stage and manage these lesions. While histological diagnosis is the gold standard, recent advancements in endoscopy, conventional imaging, functional imaging, and serum biomarkers complement histology for tailoring specific treatment options. In light of developing technology, our review sets out to characterize diagnostic and therapeutic advancements for managing gastroenteropancreatic neuroendocrine tumors, including innovations in radiolabeled peptide imaging, circulating biomarkers, and endoscopic treatment approaches adapted to different locations throughout the gastrointestinal system.en_US
dc.description.urihttps://doi.org/10.4253/wjge.v14.i5.267en_US
dc.language.isoenen_US
dc.publisherBaishideng Publishing Group Coen_US
dc.relation.ispartofWorld journal of gastrointestinal endoscopyen_US
dc.rights©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.en_US
dc.subjectGastroenteropancreatic neuroendocrine neoplasmsen_US
dc.subjectGastrointestinalen_US
dc.subjectNeuroendocrine carcinomaen_US
dc.subjectNeuroendocrine tumorsen_US
dc.subjectPancreasen_US
dc.subjectSmall intestineen_US
dc.titleCurrent updates and future directions in diagnosis and management of gastroenteropancreatic neuroendocrine neoplasms.en_US
dc.typeArticleen_US
dc.identifier.doi10.4253/wjge.v14.i5.267
dc.identifier.pmid35719897
dc.source.journaltitleWorld journal of gastrointestinal endoscopy
dc.source.volume14
dc.source.issue5
dc.source.beginpage267
dc.source.endpage290
dc.source.countryUnited States


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