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dc.contributor.authorVerhoeve, Victoria I
dc.contributor.authorFauntleroy, Tyesha D
dc.contributor.authorRisteen, Riley G
dc.contributor.authorDriscoll, Timothy P
dc.contributor.authorGillespie, Joseph J
dc.date.accessioned2022-05-24T12:37:14Z
dc.date.available2022-05-24T12:37:14Z
dc.date.issued2022-05-03
dc.identifier.urihttp://hdl.handle.net/10713/18990
dc.description.abstractThe genus Rickettsia (Alphaproteobacteria: Rickettsiales) encompasses numerous obligate intracellular species with predominantly ciliate and arthropod hosts. Notable species are pathogens transmitted to mammals by blood-feeding arthropods. Mammalian pathogenicity evolved from basal, non-pathogenic host-associations; however, some non-pathogens are closely related to pathogens. One such species, Rickettsia buchneri, is prevalent in the blacklegged tick, Ixodes scapularis. While I. scapularis transmits several pathogens to humans, it does not transmit Rickettsia pathogens. We hypothesize that R. buchneri established a mutualism with I. scapularis, blocking tick superinfection with Rickettsia pathogens.en_US
dc.description.urihttps://doi.org/10.3389/fcimb.2022.880813en_US
dc.language.isoenen_US
dc.publisherFrontiers Media S.A.en_US
dc.relationThe original contributions presented in the study are included in the article/ Supplementary Material . Further inquiries can be directed to the corresponding author.en_US
dc.relation.ispartofFrontiers in Cellular and Infection Microbiologyen_US
dc.rightsCopyright © 2022 Verhoeve, Fauntleroy, Risteen, Driscoll and Gillespie.en_US
dc.subjectIxodes scapularisen_US
dc.subjectLyme diseaseen_US
dc.subjectRickettsia buchnerien_US
dc.subjectblacklegged ticken_US
dc.subjectcontact-dependent growth inhibition systemsen_US
dc.subjectlateral gene transferen_US
dc.subjectrecombination hot spoten_US
dc.subjecttoxin-antidoteen_US
dc.titleCryptic Genes for Interbacterial Antagonism Distinguish Species Infecting Blacklegged Ticks From Other Pathogens.en_US
dc.typeArticleen_US
dc.identifier.doi10.3389/fcimb.2022.880813
dc.identifier.pmid35592653
dc.source.journaltitleFrontiers in cellular and infection microbiology
dc.source.volume12
dc.source.beginpage880813
dc.source.endpage
dc.source.countrySwitzerland


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