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dc.contributor.authorStewart, Christopher C
dc.contributor.authorO'Hara, Nathan N
dc.contributor.authorBzovsky, Sofia
dc.contributor.authorBahney, Chelsea S
dc.contributor.authorSprague, Sheila
dc.contributor.authorSlobogean, Gerard P
dc.date.accessioned2022-05-19T11:16:53Z
dc.date.available2022-05-19T11:16:53Z
dc.date.issued2022-04
dc.identifier.urihttp://hdl.handle.net/10713/18923
dc.description.abstractA total of 102 participants aged 18 to 50 years (median 28 years (interquartile range 23 to 35)), receiving an intramedullary nail for a tibial or femoral shaft fracture, were enrolled in a randomized controlled trial comparing vitamin D3 supplementation to placebo. Serum C-terminal telopeptide of type I collagen (CTX; bone resorption marker) and N-terminal propeptide of type I procollagen (P1NP; bone formation marker) were measured at baseline, six weeks, and 12 weeks post-injury. Clinical and radiological fracture healing was assessed at three months.en_US
dc.description.urihttps://doi.org/10.1302/2046-3758.114.BJR-2021-0226.R1en_US
dc.description.urihttp://www.ncbi.nlm.nih.gov/pmc/articles/pmc9057525/en_US
dc.language.isoenen_US
dc.publisherBritish Editorial Society of Bone & Joint Surgeryen_US
dc.relation.ispartofBone & Joint Researchen_US
dc.subjectBone turnover markeren_US
dc.subjectBone turnover markersen_US
dc.subjectCTXen_US
dc.subjectFractureen_US
dc.subjectP1NPen_US
dc.subjectSerumen_US
dc.subjectVitamin Den_US
dc.subjectfemoral shaft fracturesen_US
dc.subjectfemur fracturesen_US
dc.subjectfracture healingen_US
dc.subjectrandomized controlled trialen_US
dc.subjecttibiaen_US
dc.subjecttype I collagenen_US
dc.titleBone turnover markers as surrogates of fracture healing after intramedullary fixation of tibia and femur fractures.en_US
dc.typeArticleen_US
dc.identifier.doi10.1302/2046-3758.114.BJR-2021-0226.R1
dc.identifier.pmid35442058
dc.source.journaltitleBone & joint research
dc.source.volume11
dc.source.issue4
dc.source.beginpage239
dc.source.endpage250
dc.source.countryEngland


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