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dc.contributor.authorFlippo, Chelsi
dc.contributor.authorTatsi, Christina
dc.contributor.authorSinaii, Ninet
dc.contributor.authorSierra, Maria De La Luz
dc.contributor.authorBelyavskaya, Elena
dc.contributor.authorLyssikatos, Charalampos
dc.contributor.authorKeil, Meg
dc.contributor.authorSpanakis, Elias
dc.contributor.authorStratakis, Constantine A
dc.date.accessioned2022-05-10T16:57:34Z
dc.date.available2022-05-10T16:57:34Z
dc.date.issued2022-04-06
dc.identifier.urihttp://hdl.handle.net/10713/18806
dc.description.abstractForty-four patients (64% female, aged 7-55 years) were included, and 19 developed neither diabetes insipidus (DI) or syndrome of inappropriate anti-diuresis (SIADH). Thirty-three had follow-up at least 3 months postoperatively. There was no difference in peak postoperative copeptin in remission (6.1 pmol/L [4.3-12.1]) vs no remission (7.3 pmol/L [5.4-8.4], P = 0.88). Excluding those who developed DI or SIADH, there was no difference in peak postoperative copeptin in remission (10.2 pmol/L [6.9-21.0]) vs no remission (5.4 pmol/L [4.6-7.3], P = 0.20). However, a higher peak postoperative copeptin level was found in those in remission (14.6 pmol/L [±10.9] vs 5.8 (±1.4), P = 0.03]) with parametric testing. There was no difference in the Δcopeptin by remission status.en_US
dc.description.urihttps://doi.org/10.1210/jendso/bvac053en_US
dc.description.urihttp://www.ncbi.nlm.nih.gov/pmc/articles/pmc9070476/en_US
dc.language.isoenen_US
dc.publisherOxford University Pressen_US
dc.relation.ispartofJournal of the Endocrine Societyen_US
dc.rightsPublished by Oxford University Press on behalf of the Endocrine Society 2022.en_US
dc.subjectCushing diseaseen_US
dc.subjectcopeptinen_US
dc.subjectcortisolen_US
dc.subjectremissionen_US
dc.titleCopeptin Levels Before and After Transsphenoidal Surgery for Cushing Disease: A Potential Early Marker of Remission.en_US
dc.typeArticleen_US
dc.identifier.doi10.1210/jendso/bvac053
dc.identifier.pmid35528828
dc.source.journaltitleJournal of the Endocrine Society
dc.source.volume6
dc.source.issue6
dc.source.beginpagebvac053
dc.source.endpage
dc.source.countryUnited States


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