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    One-third of patients with lupus nephritis classified as complete responders continue to accrue progressive renal damage despite resolution of proteinuria.

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    Author
    Weeding, Emma
    Fava, Andrea
    Magder, Laurence
    Goldman, Daniel
    Petri, Michelle
    Date
    2022-04-09
    Journal
    Lupus Science & Medicine
    Publisher
    BMJ Publishing Group
    Type
    Article
    
    Metadata
    Show full item record
    See at
    https://doi.org/10.1136/lupus-2022-000684
    Abstract
    We conducted a single-centre study of patients diagnosed with their first episode of biopsy-proven class III, IV, and/or V LN (n=37). For each patient, eGFR trajectory was graphed over 5 years following renal biopsy. Participants were divided into those with progressive eGFR loss (eGFR slope <-5 mL/min/1.73 m2/year) versus those with stable eGFR. Participant demographics, renal biopsy features and response status at 1 year (urine protein to creatinine ratio <500 mg/g) were compared between eGFR trajectory groups.
    Rights/Terms
    © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
    Keyword
    Lupus Nephritis
    Outcome Assessment, Health Care
    Systemic Lupus Erythematosus
    Identifier to cite or link to this item
    http://hdl.handle.net/10713/18800
    ae974a485f413a2113503eed53cd6c53
    10.1136/lupus-2022-000684
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