Relative Effectiveness of MF59 Adjuvanted Trivalent Influenza Vaccine vs Nonadjuvanted Vaccines During the 2019-2020 Influenza Season.
Author
Imran, MahrukhPuig-Barbera, Joan
Ortiz, Justin R
Fischer, Lauren
O'Brien, Dan
Bonafede, Machaon
Mansi, James A
Boikos, Constantina
Date
2022-04-02Journal
Open Forum Infectious DiseasesPublisher
Oxford University PressType
Article
Metadata
Show full item recordAbstract
This retrospective cohort study used electronic medical records linked to pharmacy and medical claims data. The study population included adults age ≥65 years with a record of aIIV3, IIV4e, or HD-IIV3 vaccination. A doubly robust inverse probability of treatment weighting model was used to derive adjusted odds ratios (ORs). rVE was calculated by (1 - ORadjusted)*100 and was determined overall and separately for age subgroups. An exploratory analysis evaluated the outcome separately in inpatient and outpatient settings.Rights/Terms
© The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America.Keyword
adjuvanted influenza vaccinehigh-dose influenza vaccine
older adults
quadrivalent inactivated influenza vaccine
relative vaccine effectiveness
Identifier to cite or link to this item
http://hdl.handle.net/10713/18728ae974a485f413a2113503eed53cd6c53
10.1093/ofid/ofac167
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