Value-based evidence across health care sectors: a push for transparent real-world studies, data, and evidence dissemination.
Author
van den Broek, Remon W MMatheis, Robert J
Bright, Jennifer L
Hartog, Tessa E
Perfetto, Eleanor M
Date
2022-04-06Journal
Health Economics, Policy, and LawPublisher
Cambridge University PressType
Article
Metadata
Show full item recordAbstract
There is currently a heightened need for transparency in pharmaceutical sectors. The inclusion of real-world (RW) evidence, in addition to clinical trial evidence, in decision-making processes, was an important step forward toward a more inclusive established value proposition. This advance has introduced new transparency challenges. Increasing transparency is a critical step toward accelerating improvement in type, quality, and access to data, regardless of whether these originate from clinical trials or from RW studies. However, so far, advances in transparency have been relatively restricted to clinical trials, and there remains a lack of similar expectations or standards of transparency concerning the generation and reporting of RW data. This perspective paper aims to highlight the need for transparency concerning RW studies, data, and evidence across health care sectors, to identify areas for improvement, and provide concrete recommendations and practices for the future. Specific issues are discussed from different stakeholder perspectives, culminating in recommended actions, from individual stakeholder perspectives, for improved RW study, data, and evidence transparency. Furthermore, a list of potential guidelines for consideration by stakeholders is proposed. While recommendations from different stakeholder perspectives are made, true transparency in the processes involved in the generation, reporting, and use of RW evidence will require a concerted effort from all stakeholders across health care sectors. © The Author(s), 2022. Published by Cambridge University Press.Keyword
Health care systempeer review
real-world evidence
transparency
value assessment
value communication
Identifier to cite or link to this item
http://hdl.handle.net/10713/18684ae974a485f413a2113503eed53cd6c53
10.1017/S1744133122000056