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    Remdesivir for the Prevention of Invasive Mechanical Ventilation or Death in Coronavirus Disease 2019 (COVID-19): A Post Hoc Analysis of the Adaptive COVID-19 Treatment Trial-1 Cohort Data.

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    Author
    Paules, Catharine I
    Gallagher, Shannon K
    Rapaka, Rekha R
    Davey, Richard T
    Doernberg, Sarah B
    Grossberg, Robert
    Hynes, Noreen A
    Ponce, Philip O
    Short, William R
    Voell, Jocelyn
    Wang, Jing
    Yang, Otto O
    Wolfe, Cameron R
    Lye, David C
    Dodd, Lori E
    Benson, Constance A
    Show allShow less

    Date
    2022-04-09
    Journal
    Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
    Publisher
    Oxford University Press
    Type
    Article
    
    Metadata
    Show full item record
    See at
    https://doi.org/10.1093/cid/ciab695
    Abstract
    This post hoc analysis of the Adaptive Coronavirus Disease 2019 (COVID-19) Treatment Trial-1 (ACTT-1) shows a treatment effect of remdesivir (RDV) on progression to invasive mechanical ventilation (IMV) or death. Additionally, we create a risk profile that better predicts progression than baseline oxygen requirement alone. The highest risk group derives the greatest treatment effect from RDV.
    Rights/Terms
    © The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.
    Keyword
    ACTT-1
    COVID-19
    remdesivir
    Identifier to cite or link to this item
    http://hdl.handle.net/10713/18680
    ae974a485f413a2113503eed53cd6c53
    10.1093/cid/ciab695
    Scopus Count
    Collections
    UMB Coronavirus Publications
    UMB Open Access Articles

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