Remdesivir for the Prevention of Invasive Mechanical Ventilation or Death in Coronavirus Disease 2019 (COVID-19): A Post Hoc Analysis of the Adaptive COVID-19 Treatment Trial-1 Cohort Data.
Author
Paules, Catharine IGallagher, Shannon K
Rapaka, Rekha R
Davey, Richard T
Doernberg, Sarah B
Grossberg, Robert
Hynes, Noreen A
Ponce, Philip O
Short, William R
Voell, Jocelyn
Wang, Jing
Yang, Otto O
Wolfe, Cameron R
Lye, David C
Dodd, Lori E
Benson, Constance A
Date
2022-04-09Journal
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of AmericaPublisher
Oxford University PressType
Article
Metadata
Show full item recordAbstract
This post hoc analysis of the Adaptive Coronavirus Disease 2019 (COVID-19) Treatment Trial-1 (ACTT-1) shows a treatment effect of remdesivir (RDV) on progression to invasive mechanical ventilation (IMV) or death. Additionally, we create a risk profile that better predicts progression than baseline oxygen requirement alone. The highest risk group derives the greatest treatment effect from RDV.Rights/Terms
© The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.Identifier to cite or link to this item
http://hdl.handle.net/10713/18680ae974a485f413a2113503eed53cd6c53
10.1093/cid/ciab695
Scopus Count
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