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    Advances in Recurrent Stroke Prevention: Focus on Antithrombotic Therapies.

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    Author
    Mac Grory, Brian
    Yaghi, Shadi
    Cordonnier, Charlotte
    Sposato, Luciano A
    Romano, Jose G
    Chaturvedi, Seemant
    Date
    2022-04-14
    Journal
    Circulation Research
    Publisher
    Lippincott Williams and Wilkins
    Type
    Article
    
    Metadata
    Show full item record
    See at
    https://doi.org/10.1161/CIRCRESAHA.121.319947
    Abstract
    The past decade has seen significant advances in stroke prevention. These advances include new antithrombotic agents, new options for dyslipidemia treatment, and novel techniques for surgical stroke prevention. In addition, there is greater recognition of the benefits of multifaceted interventions, including the role of physical activity and dietary modification. Despite these advances, the aging of the population and the high prevalence of key vascular risk factors pose challenges to reducing the burden of stroke. Using a cause-based framework, current approaches to prevention of cardioembolic, cryptogenic, atherosclerotic, and small vessel disease stroke are outlined in this paper. Special emphasis is given to recent trials of antithrombotic agents, including studies that have tested combination treatments and responses according to genetic factors.
    Keyword
    atrial fibrillation
    endarterectomy, carotid
    foramen ovale, patent
    randomized controlled trial
    stroke
    Identifier to cite or link to this item
    http://hdl.handle.net/10713/18615
    ae974a485f413a2113503eed53cd6c53
    10.1161/CIRCRESAHA.121.319947
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