Advances in Recurrent Stroke Prevention: Focus on Antithrombotic Therapies.
Author
Mac Grory, BrianYaghi, Shadi
Cordonnier, Charlotte
Sposato, Luciano A
Romano, Jose G
Chaturvedi, Seemant
Date
2022-04-14Journal
Circulation ResearchPublisher
Lippincott Williams and WilkinsType
Article
Metadata
Show full item recordAbstract
The past decade has seen significant advances in stroke prevention. These advances include new antithrombotic agents, new options for dyslipidemia treatment, and novel techniques for surgical stroke prevention. In addition, there is greater recognition of the benefits of multifaceted interventions, including the role of physical activity and dietary modification. Despite these advances, the aging of the population and the high prevalence of key vascular risk factors pose challenges to reducing the burden of stroke. Using a cause-based framework, current approaches to prevention of cardioembolic, cryptogenic, atherosclerotic, and small vessel disease stroke are outlined in this paper. Special emphasis is given to recent trials of antithrombotic agents, including studies that have tested combination treatments and responses according to genetic factors.Keyword
atrial fibrillationendarterectomy, carotid
foramen ovale, patent
randomized controlled trial
stroke
Identifier to cite or link to this item
http://hdl.handle.net/10713/18615ae974a485f413a2113503eed53cd6c53
10.1161/CIRCRESAHA.121.319947
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