Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Seroprevalence in Decedents Undergoing Forensic Postmortem Examination: Feasibility for Real-Time Pandemic Surveillance.
Author
Coburn, Sally BManabe, Yukari C
Laeyendecker, Oliver
Sherman, Susan G
Baker, Owen R
Quinn, Thomas C
Graham, Lindsey A
Dennis Thomas, F
Southall, Pamela
Weedn, Victor W
Ehsani, Johnathon
Klock, Ethan
Li, Rong
Shields, Wendy C
Michael, Jeffrey Paul
Li, Ling
Althoff, Keri N
Date
2022-04-10Journal
Open Forum Infectious DiseasesPublisher
Oxford University PressType
Article
Metadata
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Among 1906 decedents, 305 (16%) were positive for SARS-CoV-2 antibodies. Monthly seroprevalence increased from 11% to 22% over time and was consistently higher than state-level estimates of testing positivity. Hispanic ethnicity was associated with 2- to 3.2-fold higher seropositivity (P < .05) irrespective of sex. Deaths due to motor vehicle crash were associated with 62% increased seropositivity (aPR, 1.62 [95% CI, 1.15-2.28]) vs natural manner of death. Though seroprevalence was lower in decedents of illicit drug overdose vs nonoverdose in early months, this shifted, and seroprevalence was comparable by November 2020.Rights/Terms
© The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America.Identifier to cite or link to this item
http://hdl.handle.net/10713/18579ae974a485f413a2113503eed53cd6c53
10.1093/ofid/ofac142
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