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    Homologous and Heterologous Covid-19 Booster Vaccinations.

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    Author
    Atmar, Robert L
    Lyke, Kirsten E
    Deming, Meagan E
    Jackson, Lisa A
    Branche, Angela R
    El Sahly, Hana M
    Rostad, Christina A
    Martin, Judith M
    Johnston, Christine
    Rupp, Richard E
    Mulligan, Mark J
    Brady, Rebecca C
    Frenck, Robert W
    Bäcker, Martín
    Kottkamp, Angelica C
    Babu, Tara M
    Rajakumar, Kumaravel
    Edupuganti, Srilatha
    Dobrzynski, David
    Coler, Rhea N
    Posavad, Christine M
    Archer, Janet I
    Crandon, Sonja
    Nayak, Seema U
    Szydlo, Daniel
    Zemanek, Jillian A
    Dominguez Islas, Clara P
    Brown, Elizabeth R
    Suthar, Mehul S
    McElrath, M Juliana
    McDermott, Adrian B
    O'Connell, Sarah E
    Montefiori, David C
    Eaton, Amanda
    Neuzil, Kathleen M
    Stephens, David S
    Roberts, Paul C
    Beigel, John H
    Show allShow less

    Date
    2022-01-26
    Journal
    New England Journal of Medicine
    Publisher
    Massachusetts Medical Society
    Type
    Article
    
    Metadata
    Show full item record
    See at
    https://doi.org/10.1056/NEJMoa2116414
    https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/35081293/
    Abstract
    In this phase 1-2, open-label clinical trial conducted at 10 sites in the United States, adults who had completed a Covid-19 vaccine regimen at least 12 weeks earlier and had no reported history of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection received a booster injection with one of three vaccines: mRNA-1273 (Moderna) at a dose of 100 μg, Ad26.COV2.S (Johnson & Johnson-Janssen) at a dose of 5×1010 virus particles, or BNT162b2 (Pfizer-BioNTech) at a dose of 30 μg. The primary end points were safety, reactogenicity, and humoral immunogenicity on trial days 15 and 29.
    Rights/Terms
    Copyright © 2022 Massachusetts Medical Society.
    Identifier to cite or link to this item
    http://hdl.handle.net/10713/18021
    ae974a485f413a2113503eed53cd6c53
    10.1056/NEJMoa2116414
    Scopus Count
    Collections
    UMB Coronavirus Publications
    UMB Open Access Articles

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