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dc.contributor.authorKohl, Patricia L
dc.contributor.authorGyimah, Emmanuel A
dc.contributor.authorDiaz, Jenna
dc.contributor.authorKuhlmann, F Matthew
dc.contributor.authorDulience, Sherlie Jean-Louis
dc.contributor.authorEmbaye, Fithi
dc.contributor.authorBrown, Derek S
dc.contributor.authorGuo, Shenyang
dc.contributor.authorLuby, Joan L
dc.contributor.authorNicholas, Jennifer L
dc.contributor.authorTurner, Jay
dc.contributor.authorChapnick, Melissa
dc.contributor.authorPierre, Joseline Marhone
dc.contributor.authorBoncy, Jacques
dc.contributor.authorSt Fleur, Rony
dc.contributor.authorBlack, Maureen M
dc.contributor.authorIannotti, Lora L
dc.date.accessioned2022-01-28T15:37:58Z
dc.date.available2022-01-28T15:37:58Z
dc.date.issued2022-01-21
dc.identifier.urihttp://hdl.handle.net/10713/17802
dc.description.abstractBackground: Poor child growth and development outcomes stem from complex relationships encompassing biological, behavioral, social, and environmental conditions. However, there is a dearth of research on integrated approaches targeting these interwoven factors. The Grandi Byen study seeks to fill this research gap through a three-arm longitudinal randomized controlled trial which will evaluate the impact of an integrated nutrition, responsive parenting, and WASH (water, sanitation and hygiene) intervention on holistic child growth and development. Methods: We will recruit 600 mother-infant dyads living in Cap-Haitien, Haiti and randomize them equally into one of the following groups: 1) standard well-baby care; 2) nutritional intervention (one egg per day for 6 months); and 3) multicomponent Grandi Byen intervention (responsive parenting, nutrition, WASH + one egg per day for 6 months). Primary outcomes include child growth as well as cognitive, language, motor, and social-emotional development. The study also assesses other indicators of child health (bone maturation, brain growth, diarrheal morbidity and allergies, dietary intake, nutrient biomarkers) along with responsive parenting as mediating factors influencing the primary outcomes. An economic evaluation will assess the feasibility of large-scale implementation of the interventions. Discussion: This study builds on research highlighting the importance of responsive parenting interventions on overall child health, as well as evidence demonstrating that providing an egg daily to infants during the complementary feeding period can prevent stunted growth. The multicomponent Grandi Byen intervention may provide evidence of synergistic or mediating effects of an egg intervention with instruction on psychoeducational parenting and WASH on child growth and development. Grandi Byen presents key innovations with implications for the well-being of children living in poverty globally. Trial registration: NCT04785352 . Registered March 5, 2021 at https://clinicaltrials.gov/.en_US
dc.description.urihttps://doi.org/10.1186/s12887-021-03089-xen_US
dc.language.isoenen_US
dc.publisherSpringer Natureen_US
dc.relation.ispartofBMC Pediatricsen_US
dc.rights© 2022. The Author(s).en_US
dc.subjectChild developmenten_US
dc.subjectIntegrated parenting interventionen_US
dc.subjectNutritionen_US
dc.subjectResponsive parentingen_US
dc.subjectStuntingen_US
dc.titleGrandi Byen-supporting child growth and development through integrated, responsive parenting, nutrition and hygiene: study protocol for a randomized controlled trial.en_US
dc.typeArticleen_US
dc.identifier.doi10.1186/s12887-021-03089-x
dc.identifier.pmid35062907
dc.source.journaltitleBMC pediatrics
dc.source.volume22
dc.source.issue1
dc.source.beginpage54
dc.source.endpage
dc.source.countryEngland


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