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dc.contributor.authorYanez Touzet, Alvaro
dc.contributor.authorBhatti, Aniqah
dc.contributor.authorDohle, Esmee
dc.contributor.authorBhatti, Faheem
dc.contributor.authorLee, Keng Siang
dc.contributor.authorFurlan, Julio C
dc.contributor.authorFehlings, Michael G
dc.contributor.authorHarrop, James S
dc.contributor.authorZipser, Carl Moritz
dc.contributor.authorRodrigues-Pinto, Ricardo
dc.contributor.authorMilligan, James
dc.contributor.authorSarewitz, Ellen
dc.contributor.authorCurt, Armin
dc.contributor.authorRahimi-Movaghar, Vafa
dc.contributor.authorAarabi, Bizhan
dc.contributor.authorBoerger, Timothy F
dc.contributor.authorTetreault, Lindsay
dc.contributor.authorChen, Robert
dc.contributor.authorGuest, James D
dc.contributor.authorKalsi-Ryan, Sukhvinder
dc.contributor.authorMcNair, Angus Gk
dc.contributor.authorKotter, Mark
dc.contributor.authorDavies, Benjamin
dc.date.accessioned2022-01-24T15:02:41Z
dc.date.available2022-01-24T15:02:41Z
dc.date.issued2022-01-19
dc.identifier.urihttp://hdl.handle.net/10713/17750
dc.description.abstractObjectives: To evaluate the measurement properties of outcome measures currently used in the assessment of degenerative cervical myelopathy (DCM) for clinical research. Design: Systematic review DATA SOURCES: MEDLINE and EMBASE were searched through 4 August 2020. Eligibility criteria: Primary clinical research published in English and whose primary purpose was to evaluate the measurement properties or clinically important differences of instruments used in DCM. Data extraction and synthesis: Psychometric properties and clinically important differences were both extracted from each study, assessed for risk of bias and presented in accordance with the Consensus-based Standards for the selection of health Measurement Instruments criteria. Results: Twenty-nine outcome instruments were identified from 52 studies published between 1999 and 2020. They measured neuromuscular function (16 instruments), life impact (five instruments), pain (five instruments) and radiological scoring (five instruments). No instrument had evaluations for all 10 measurement properties and <50% had assessments for all three domains (ie, reliability, validity and responsiveness). There was a paucity of high-quality evidence. Notably, there were no studies that reported on structural validity and no high-quality evidence that discussed content validity. In this context, we identified nine instruments that are interpretable by clinicians: the arm and neck pain scores; the 12-item and 36-item short form health surveys; the Japanese Orthopaedic Association (JOA) score, modified JOA and JOA Cervical Myelopathy Evaluation Questionnaire; the neck disability index; and the visual analogue scale for pain. These include six scores with barriers to application and one score with insufficient criterion and construct validity. Conclusions: This review aggregates studies evaluating outcome measures used to assess patients with DCM. Overall, there is a need for a set of agreed tools to measure outcomes in DCM. These findings will be used to inform the development of a core measurement set as part of AO Spine RECODE-DCM.en_US
dc.description.urihttps://doi.org/10.1136/bmjopen-2021-057650en_US
dc.language.isoenen_US
dc.publisherBMJ Publishing Groupen_US
dc.relation.ispartofBMJ Openen_US
dc.rights© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.en_US
dc.subjectcervical spondylotic myelopathyen_US
dc.subjectcore measurement seten_US
dc.subjectdegenerative cervical myelopathyen_US
dc.subjectoutcome measuresen_US
dc.subjectspinal cord compressionen_US
dc.titleClinical outcome measures and their evidence base in degenerative cervical myelopathy: a systematic review to inform a core measurement set (AO Spine RECODE-DCM).en_US
dc.typeArticleen_US
dc.identifier.doi10.1136/bmjopen-2021-057650
dc.identifier.pmid35046007
dc.source.journaltitleBMJ open
dc.source.volume12
dc.source.issue1
dc.source.beginpagee057650
dc.source.endpage
dc.source.countryEngland


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