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    Advancing Clinical Trials in Nursing Homes: A Proposed Roadmap to Success.

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    Author
    Gurwitz, Jerry H
    Quinn, Charlene C
    Abi-Elias, Ivan H
    Adams, Alyce S
    Bartel, Rosie
    Bonner, Alice
    Boxer, Rebecca
    Delude, Christopher
    Gifford, David
    Hanson, Bruce
    Ito, Kouta
    Jain, Paavani
    Magaziner, Jay S
    Mazor, Kathleen M
    Mitchell, Susan L
    Mody, Lona
    Nace, David
    Ouslander, Joseph
    Reifsnyder, JoAnne
    Resnick, Barbara
    Zimmerman, Sheryl
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    Date
    2021-12-22
    Journal
    Journal of the American Medical Directors Association
    Publisher
    Elsevier
    Type
    Article
    
    Metadata
    Show full item record
    See at
    https://doi.org/10.1016/j.jamda.2021.11.034
    Abstract
    An effective clinical research effort in nursing homes to address prevention and treatment of COVID-19 faced overwhelming challenges. Under the Health Care Systems Research Network-Older Americans Independence Centers AGING Initiative, a multidisciplinary Stakeholder Advisory Panel was convened to develop recommendations to improve the capability of the clinical research enterprise in US nursing homes. The Panel considered the nursing home as a setting for clinical trials, reviewed the current state of clinical trials in nursing homes, and ultimately developed recommendations for the establishment of a nursing home clinical trials research network that would be centrally supported and administered. This report summarizes the Panel's recommendations, which were developed in alignment with the following core principles: build on available research infrastructure where appropriate; leverage existing productive partnerships of researchers with groups of nursing homes and nursing home corporations; encompass both efficacy and effectiveness clinical trials; be responsive to a broad range of stakeholders including nursing home residents and their care partners; be relevant to an expansive range of clinical and health care delivery research questions; be able to pivot as necessary to changing research priorities and circumstances; create a pathway for industry-sponsored research as appropriate; invest in strategies to increase diversity in study populations and the research workforce; and foster the development of the next generation of nursing home researchers. © 2021 AMDA – The Society for Post-Acute and Long-Term Care Medicine
    Rights/Terms
    Copyright © 2021 AMDA – The Society for Post-Acute and Long-Term Care Medicine. Published by Elsevier Inc. All rights reserved.
    Keyword
    COVID-19
    Nursing homes
    clinical trials
    long-term care
    pandemic
    Identifier to cite or link to this item
    http://hdl.handle.net/10713/17603
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.jamda.2021.11.034
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