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dc.contributor.authorHardy, Naomi L
dc.contributor.authorLuethy, Paul M
dc.date.accessioned2022-01-19T14:29:23Z
dc.date.available2022-01-19T14:29:23Z
dc.date.issued2021-11
dc.identifier.urihttp://hdl.handle.net/10713/17573
dc.description.abstractBACKGROUND: An evolving COVID-19 testing landscape and issues with test supply allocation, especially in the current pandemic, has made it challenging for ordering providers. We audited orders of the Xpert® Xpress SARS-CoV-2 PCR with reverse transcription (RT-PCR) platform-the fastest of several other testing modalities available-to illuminate these challenges utilizing a multidisciplinary laboratory professional team consisting of a pathology resident and microbiology laboratory director. METHODS: Retrospective review of the first 5 hundred Xpert Xpress SARS-CoV-2 RT-PCR test orders from a 2-week period to determine test appropriateness based on the following indications: emergency surgery, emergent obstetric procedures, initial behavioral health admission, and later including discharge to skilled care facilities and pediatric admissions. Our hypothesis was that a significant proportion of orders for this testing platform were inappropriate. RESULTS: On review, a significant proportion of orders were incorrect, with 69.8% (n = 349, P < 0.0001) not meeting indications for rapid testing. Of all orders, 249 designated as emergency surgery were inappropriate, with 49.0% of those orders never proceeding with any surgical intervention; most of these were trauma related (64.6% were orders associated with a trauma unit). CONCLUSIONS: Significant, pervasive inappropriate ordering practices were identified at this center. A laboratory professional team can be key to identifying problems in testing and play a significant role in combating inappropriate test utilization.en_US
dc.description.urihttps://doi.org/10.1093/jalm/jfab081en_US
dc.description.urihttp://www.ncbi.nlm.nih.gov/pmc/articles/pmc8344747/en_US
dc.language.isoenen_US
dc.publisherOxford University Pressen_US
dc.relation.ispartofJournal of Applied Laboratory Medicineen_US
dc.rights© American Association for Clinical Chemistry 2021. All rights reserved. For permissions, please email: journals.permissions@oup.com.en_US
dc.subjectinterlaboratory performanceen_US
dc.subjectlaboratory managementen_US
dc.subjectlaboratory methods and toolsen_US
dc.subjectproficiency testingen_US
dc.titleEvaluation of Inappropriate COVID-19 RT-PCR Test Utilization at an Academic Medical Center.en_US
dc.typeArticleen_US
dc.identifier.doi10.1093/jalm/jfab081
dc.identifier.pmid34191020
dc.source.journaltitleThe journal of applied laboratory medicine
dc.source.volume6
dc.source.issue6
dc.source.beginpage1484
dc.source.endpage1491
dc.source.countryEngland


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