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    Rapid identification of 1-positive from patient urine using a novel lipid-based MALDI-TOF-MS assay.

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    Author
    Smith, Richard D
    Izac, Jerilyn R
    Ha, Michael
    Yang, Hyojik
    Johnson, J Kristie
    Ernst, Robert K
    Date
    2021-12-17
    Journal
    Access Microbiology
    Publisher
    American Society for Microbiology
    Type
    Article
    
    Metadata
    Show full item record
    See at
    https://doi.org/10.1099/acmi.0.000309
    Abstract
    Mobilized colistin resistance (mcr) genes confer resistance to colistin, a last-resort antibiotic for multidrug-resistant Gram-negative infections. In this case report, we describe a novel lipid-based matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) diagnostic used to rapidly identify an mcr-1-positive Escherichia coli directly from a patient with a urinary tract infection without the need for ex vivo growth.
    Rights/Terms
    © 2021 The Authors.
    Keyword
    Escherichia coli
    MALDI-TOF MS
    mobilized colistin resistance gene
    urinary tract infection
    Identifier to cite or link to this item
    http://hdl.handle.net/10713/17538
    ae974a485f413a2113503eed53cd6c53
    10.1099/acmi.0.000309
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