Show simple item record

dc.contributor.authorHaac, Bryce E.
dc.contributor.authorO’Hara, Nathan N.
dc.contributor.authorManson, Theodore T.
dc.contributor.authorSlobogean, Gerard P.
dc.contributor.authorCastillo, Renan C.
dc.contributor.authorO’Toole, Robert V.
dc.contributor.authorStein, Deborah M.
dc.date.accessioned2021-11-16T13:53:00Z
dc.date.available2021-11-16T13:53:00Z
dc.date.issued2021-09-15
dc.identifier.urihttp://hdl.handle.net/10713/17130
dc.description.abstractObjectives: To compare inpatient compliance with venous thromboembolism prophylaxis regimens. Design: A secondary analysis of patients enrolled in the ADAPT (A Different Approach to Preventing Thrombosis) randomized controlled trial. Setting: Level I trauma center. Patients/participants: Patients with operative extremity or any pelvic or acetabular fracture requiring venous thromboembolism prophylaxis. Intervention: We compared patients randomized to receive either low molecular weight heparin (LMWH) 30 mg or aspirin 81 mg BID during their inpatient admission. Main outcome measurements: The primary outcome measure was the number of doses missed compared with prescribed number of doses. Results: A total of 329 patients were randomized to receive either LMWH 30 mg BID (164 patients) or aspirin 81 mg BID (165 patients). No differences observed in percentage of patients who missed a dose (aspirin: 41.2% vs LMWH: 43.3%, P = .7) or mean number of missed doses (0.6 vs 0.7 doses, P = .4). The majority of patients (57.8%, n = 190) did not miss any doses. Missed doses were often associated with an operation. Conclusions: These data should reassure clinicians that inpatient compliance is similar for low molecular weight heparin and aspirin regimens.en_US
dc.description.urihttps://doi.org/10.1097/oi9.0000000000000150en_US
dc.language.isoenen_US
dc.publisherOvid Technologies (Wolters Kluwer Health)en_US
dc.relation.ispartofOTA Internationalen_US
dc.subjectaspirinen_US
dc.subjectlow molecular weight heparinen_US
dc.subjecttraumaen_US
dc.subjectvenous thromboembolism prophylaxisen_US
dc.titleInpatient compliance with venous thromboembolism prophylaxis after orthopaedic trauma: results from a randomized controlled trial of aspirin versus low molecular weight heparinen_US
dc.typeArticleen_US
dc.identifier.doi10.1097/oi9.0000000000000150
dc.source.volume4
dc.source.issue4
dc.source.beginpagee150


This item appears in the following Collection(s)

Show simple item record