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dc.contributor.authorVanRyzin, Jonathan W
dc.date.accessioned2021-11-16T13:18:42Z
dc.date.available2021-11-16T13:18:42Z
dc.date.issued2021-10-20
dc.identifier.urihttp://hdl.handle.net/10713/17125
dc.description.abstractMicroglia, the innate immune cells of the brain, are indispensable for proper brain development. As professional phagocytes, microglia engulf other cells within distinct developmental niches to sculpt the architecture of the brain. Here, I highlight the age-, brain region-, and substrate-dependent diversity of developmental phagocytosis, and pose the idea that phagocytosis may, in turn, drive changes in microglia phenotype. Ultimately, phagocytosis might be just as important for shaping microglia function as it is for shaping the brain.en_US
dc.description.urihttps://doi.org/10.1016/j.bbih.2021.100373en_US
dc.language.isoenen_US
dc.publisherElsevier Ltd.en_US
dc.relation.ispartofBrain, Behavior, & Immunity - Healthen_US
dc.rights© 2021 The Author.en_US
dc.subjectBehavioren_US
dc.subjectBrain developmenten_US
dc.subjectMicrogliaen_US
dc.subjectPhagocytosisen_US
dc.subjectTrained immunityen_US
dc.titlePhagocytic microglia in development: Are they what they eat?en_US
dc.typeArticleen_US
dc.identifier.doi10.1016/j.bbih.2021.100373
dc.identifier.pmid34761244
dc.source.volume18
dc.source.beginpage100373
dc.source.endpage
dc.source.countryUnited States


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