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dc.contributor.authorCaffes, Nicholas
dc.contributor.authorWenger, Nicole
dc.contributor.authorCannarsa, Gregory
dc.contributor.authorOliver, Jeffrey
dc.contributor.authorOnwukwe, Chimdiya
dc.contributor.authorGandhi, Dheeraj
dc.contributor.authorSimard, J Marc
dc.date.accessioned2021-10-28T18:16:36Z
dc.date.available2021-10-28T18:16:36Z
dc.date.issued2021-10-19en_US
dc.identifier.urihttp://hdl.handle.net/10713/17006
dc.description.abstractUnruptured cerebral aneurysms are increasingly identified in elderly patients as the global life expectancy continues to rise and non-invasive vascular imaging becomes more prevalent. The optimal management of unruptured aneurysms in elderly patients remains controversial. Variability in life expectancy, comorbidities and rupture risk coupled with heterogenous endovascular and surgical treatments contribute to a paucity of clear guidelines, and current management is highly individualized. Elderly patients present unique considerations including frailty, cognitive dysfunction, vasculopathy, reduced life expectancy and overall worse prognosis in case of rupture which shape the risks and likelihood of success of endovascular and microsurgical treatment. In this review, we provide a comprehensive overview of unruptured cerebral aneurysms in the elderly, with a particular focus on the natural history, key challenges associated with advanced age, management and future innovations to further refine treatment.en_US
dc.description.urihttps://doi.org/10.1080/07853890.2021.1990393en_US
dc.description.urihttp://www.ncbi.nlm.nih.gov/pmc/articles/pmc8530485/en_US
dc.language.isoenen_US
dc.publisherFinnish Medical Society Duodecimen_US
dc.relation.ispartofAnnals of medicineen_US
dc.subjectElderlyen_US
dc.subjectaneurysmsen_US
dc.subjectchallengesen_US
dc.subjectendovascularen_US
dc.subjectmicrosurgeryen_US
dc.subjectunruptureden_US
dc.titleUnruptured cerebral aneurysms in elderly patients: key challenges and managementen_US
dc.typeArticleen_US
dc.identifier.doi10.1080/07853890.2021.1990393
dc.identifier.pmid34664535
dc.source.volume53
dc.source.issue1
dc.source.beginpage1839
dc.source.endpage1849
dc.source.countryEngland


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