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dc.contributor.authorCawthon, Peggy M
dc.contributor.authorPatel, Sheena M
dc.contributor.authorKritchevsky, Stephen B
dc.contributor.authorNewman, Anne B
dc.contributor.authorSantanasto, Adam
dc.contributor.authorKiel, Douglas P
dc.contributor.authorTravison, Thomas G
dc.contributor.authorLane, Nancy
dc.contributor.authorCummings, Steven R
dc.contributor.authorOrwoll, Eric S
dc.contributor.authorDuchowny, Kate A
dc.contributor.authorKwok, Timothy
dc.contributor.authorHirani, Vasant
dc.contributor.authorSchousboe, John
dc.contributor.authorKarlsson, Magnus K
dc.contributor.authorMellström, Dan
dc.contributor.authorOhlsson, Claes
dc.contributor.authorLjunggren, Östen
dc.contributor.authorXue, Qian-Li
dc.contributor.authorShardell, Michelle
dc.contributor.authorJordan, Joanne M
dc.contributor.authorPencina, Karol M
dc.contributor.authorFielding, Roger A
dc.contributor.authorMagaziner, Jay
dc.contributor.authorCorrea-de-Araujo, Rosaly
dc.contributor.authorBhasin, Shalender
dc.contributor.authorManini, Todd M
dc.date.accessioned2021-10-25T18:59:27Z
dc.date.available2021-10-25T18:59:27Z
dc.date.issued2021-06-24
dc.identifier.urihttp://hdl.handle.net/10713/16952
dc.description.abstractBackground Cut-points to define slow walking speed have largely been derived from expert opinion. Methods Study participants (13 589 men and 5043 women aged ≥65years) had walking speed (m/s) measured over 4-6 m (mean ± SD: 1.20 ± 0.27 m/s in men and 0.94 ± 0.24 m/s in women.) Mobility limitation was defined as any self-reported difficulty with walking approximately 1/4 mile (prevalence: 12.6% men, 26.4% women). Sex-stratified classification and regression tree (CART) models with 10-fold cross-validation identified walking speed cut-points that optimally discriminated those who reported mobility limitation from those who did not. Results Among 5043 women, CART analysis identified 2 cut-points, classifying 4144 (82.2%) with walking speed ≥0.75 m/s, which we labeled as "fast"; 478 (9.5%) as "intermediate" (walking speed ≥0.62 m/s but <0.75 m/s); and 421 (8.3%) as "slow" (walking speed <0.62 m/s). Among 13 589 men, CART analysis identified 3 cut-points, classifying 10 001 (73.6%) with walking speed ≥1.00 m/s ("very fast"); 2901 (21.3%) as "fast" (walking speed ≥0.74 m/s but <1.00 m/s); 497 (3.7%) as "intermediate" (walking speed ≥0.57 m/s but <0.74 m/s); and 190 (1.4%) as "slow" (walking speed <0.57 m/s). Prevalence of self-reported mobility limitation was lowest in the "fast" or "very fast" (11% for men and 19% for women) and highest in the "slow" (60.5% in men and 71.0% in women). Rounding the 2 slower cut-points to 0.60 m/s and 0.75 m/s reclassified very few participants. Conclusions Cut-points in walking speed of approximately 0.60 m/s and 0.75 m/s discriminate those with self-reported mobility limitation from those without.en_US
dc.description.urihttps://escholarship.org/uc/item/56g1x17ren_US
dc.description.urihttps://doi.org/10.1093/gerona/glab183en_US
dc.language.isoenen_US
dc.publisherOxford University Pressen_US
dc.relation.ispartofJournals of Gerontology. Series A, Biological Sciences and Medical Sciencesen_US
dc.rights© The Author(s) 2021. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.en_US
dc.subjectClassification and regression treesen_US
dc.subjectGait speeden_US
dc.subjectMobility limitationen_US
dc.titleWhat Cut-Point in Gait Speed Best Discriminates Community-Dwelling Older Adults With Mobility Complaints From Those Without? A Pooled Analysis From the Sarcopenia Definitions and Outcomes Consortiumen_US
dc.typeArticleen_US
dc.identifier.doi10.1093/gerona/glab183
dc.identifier.pmid34166490
dc.source.volume76
dc.source.issue10
dc.source.beginpagee321
dc.source.endpagee327
dc.source.countryUnited States


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