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    What Cut-Point in Gait Speed Best Discriminates Community-Dwelling Older Adults With Mobility Complaints From Those Without? A Pooled Analysis From the Sarcopenia Definitions and Outcomes Consortium

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    Author
    Cawthon, Peggy M
    Patel, Sheena M
    Kritchevsky, Stephen B
    Newman, Anne B
    Santanasto, Adam
    Kiel, Douglas P
    Travison, Thomas G
    Lane, Nancy
    Cummings, Steven R
    Orwoll, Eric S
    Duchowny, Kate A
    Kwok, Timothy
    Hirani, Vasant
    Schousboe, John
    Karlsson, Magnus K
    Mellström, Dan
    Ohlsson, Claes
    Ljunggren, Östen
    Xue, Qian-Li
    Shardell, Michelle
    Jordan, Joanne M
    Pencina, Karol M
    Fielding, Roger A
    Magaziner, Jay
    Correa-de-Araujo, Rosaly
    Bhasin, Shalender
    Manini, Todd M
    Show allShow less

    Date
    2021-06-24
    Journal
    Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
    Publisher
    Oxford University Press
    Type
    Article
    
    Metadata
    Show full item record
    See at
    https://escholarship.org/uc/item/56g1x17r
    https://doi.org/10.1093/gerona/glab183
    Abstract
    Background Cut-points to define slow walking speed have largely been derived from expert opinion. Methods Study participants (13 589 men and 5043 women aged ≥65years) had walking speed (m/s) measured over 4-6 m (mean ± SD: 1.20 ± 0.27 m/s in men and 0.94 ± 0.24 m/s in women.) Mobility limitation was defined as any self-reported difficulty with walking approximately 1/4 mile (prevalence: 12.6% men, 26.4% women). Sex-stratified classification and regression tree (CART) models with 10-fold cross-validation identified walking speed cut-points that optimally discriminated those who reported mobility limitation from those who did not. Results Among 5043 women, CART analysis identified 2 cut-points, classifying 4144 (82.2%) with walking speed ≥0.75 m/s, which we labeled as "fast"; 478 (9.5%) as "intermediate" (walking speed ≥0.62 m/s but <0.75 m/s); and 421 (8.3%) as "slow" (walking speed <0.62 m/s). Among 13 589 men, CART analysis identified 3 cut-points, classifying 10 001 (73.6%) with walking speed ≥1.00 m/s ("very fast"); 2901 (21.3%) as "fast" (walking speed ≥0.74 m/s but <1.00 m/s); 497 (3.7%) as "intermediate" (walking speed ≥0.57 m/s but <0.74 m/s); and 190 (1.4%) as "slow" (walking speed <0.57 m/s). Prevalence of self-reported mobility limitation was lowest in the "fast" or "very fast" (11% for men and 19% for women) and highest in the "slow" (60.5% in men and 71.0% in women). Rounding the 2 slower cut-points to 0.60 m/s and 0.75 m/s reclassified very few participants. Conclusions Cut-points in walking speed of approximately 0.60 m/s and 0.75 m/s discriminate those with self-reported mobility limitation from those without.
    Rights/Terms
    © The Author(s) 2021. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
    Keyword
    Classification and regression trees
    Gait speed
    Mobility limitation
    Identifier to cite or link to this item
    http://hdl.handle.net/10713/16952
    ae974a485f413a2113503eed53cd6c53
    10.1093/gerona/glab183
    Scopus Count
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