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dc.contributor.authorLu, Chun-Li
dc.contributor.authorLi, Xun
dc.contributor.authorZhou, Hong-Mei
dc.contributor.authorZhang, Chi
dc.contributor.authorYang, Ya-Yue
dc.contributor.authorFeng, Ru-Li
dc.contributor.authorLong, Chao-Jun
dc.contributor.authorDeng, Fang-Yuan
dc.contributor.authorLi, Jing-Chun
dc.contributor.authorCao, Ze-Ming
dc.contributor.authorMao, Qi-Yuan
dc.contributor.authorZhu, Jin-Pu
dc.contributor.authorHong, Yan-Fei
dc.contributor.authorHuang, Shou-Yu
dc.contributor.authorQiu, Jia-Ying
dc.contributor.authorLiu, Yi-Xiu
dc.contributor.authorWang, Ying
dc.contributor.authorYan, Yu-Qian
dc.contributor.authorDong, Jia-Min
dc.contributor.authorLuo, Yu-Xin
dc.contributor.authorChen, Yun-Meng
dc.contributor.authorGuan, Ying-Jie
dc.contributor.authorWieland, Lisa Susan
dc.contributor.authorRobinson, Nicola
dc.contributor.authorLiu, Jian-Ping
dc.date.accessioned2021-07-19T19:45:55Z
dc.date.available2021-07-19T19:45:55Z
dc.identifier.urihttp://hdl.handle.net/10713/16206
dc.description.abstractBackground: Traditional Chinese medicine (TCM) is widely integrated into cancer care in China. An overview in 2011 identified 2384 randomized and non-randomized controlled trials (RCTs, non-RCTs) on TCM for cancer published in the Chinese literature. This article summarizes updated evidence of RCTs on TCM for cancer care. Methods: We searched 4 main Chinese databases: China National Knowledge Infrastructure, Chinese Scientific Journal Database, SinoMed, and Wanfang. RCTs on TCM used in cancer care were analyzed in this bibliometric study. Results: Of 5834 RCTs (477 157 cancer patients), only 62 RCTs were indexed in MEDLINE. The top 3 cancers treated were lung, stomach, and breast cancer. About 4752 RCTs (81.45%) tested TCM combined with conventional treatment, and 1082 RCTs (18.55%) used TCM alone for treating symptoms and side-effects. Herbal medicine was the most frequently used TCM modality (5087 RCTs; 87.20%). The most frequently reported outcome was symptom improvement (3712 RCTs; 63.63%) followed by quality of life (2725 RCTs; 46.71%), and biomarkers (2384 RCTs; 40.86%). The majority of RCTs (4051; 69.44%) concluded there were beneficial effects using either TCM alone or TCM plus conventional treatment compared with conventional treatment. Conclusion: Substantial randomized trials demonstrated different types/stages of cancer were treated by various TCM modalities, alone or in combination with conventional medicine. Further evaluation on the effects and safety of TCM modalities focusing on outcomes such as quality of life is required.en_US
dc.description.urihttps://doi.org/10.1177/15347354211031650en_US
dc.language.isoenen_US
dc.publisherSAGE Publications Inc.en_US
dc.relation.ispartofIntegrative Cancer Therapiesen_US
dc.subjectChinese literatureen_US
dc.subjectTraditional Chinese medicineen_US
dc.subjectbibliometric analysisen_US
dc.subjectcanceren_US
dc.subjectclinical evidenceen_US
dc.subjectrandomized controlled trialsen_US
dc.titleTraditional Chinese Medicine in Cancer Care: An Overview of 5834 Randomized Controlled Trials Published in Chineseen_US
dc.typeArticleen_US
dc.identifier.doi10.1177/15347354211031650
dc.identifier.pmid34261372
dc.source.volume20
dc.source.beginpage15347354211031650
dc.source.endpage
dc.identifier.eissn1552-695X
dc.source.countryUnited States
dc.identifier.journalIntegrative cancer therapies


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