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dc.contributor.authorDiaz-Abad, Montserrat
dc.contributor.authorRobinett, Kathryn S.
dc.contributor.authorLasso-Pirot, Anayansi
dc.contributor.authorLegesse, Teklu B.
dc.contributor.authorKhambaty, Mariam
dc.date.accessioned2021-07-12T13:15:44Z
dc.date.available2021-07-12T13:15:44Z
dc.date.issued2021-06-18
dc.identifier.urihttp://hdl.handle.net/10713/16163
dc.description.abstractHuman Immunodeficiency Virus (HIV)-related Opportunistic Infections (OI), including Pneumocystis jiroveci pneumonia (PCP), have become much less commonplace with anti-retroviral therapy (ART). Despite this, OIs are still common and it is important to remain vigilant for their presence and be aware of how ART and OI chemoprophylaxis may lead to atypical disease presentations. We present the case of a 51-year-old woman with HIV and CD4+ T helper lymphocytes cell count > 200 cells/ul on both ART and trimethoprim/sulfamethoxazole prophylaxis who presented with cavitating lung masses, mediastinal lymphadenopathy and pleural effusions. Negative bronchoalveolar lavage (BAL) and transbronchial biopsy (TBBx) prompted a second diagnostic procedure with a transthoracic core needle biopsy; the final diagnosis was granulomatous PCP. This case showcases a very rare presentation of PCP, with both large cavitating lung masses on imaging and granulomatous reaction on pathology, as well as the challenge of a potentially missed diagnosis with negative BAL and TBBx requiring transthoracic core needle biopsy for a final diagnosis. © 2021 Diaz-Abad et al.en_US
dc.description.urihttps://doi.org/10.2174/1874306402115010019en_US
dc.language.isoenen_US
dc.publisherBentham Science Publishersen_US
dc.relation.ispartofOpen Respiratory Medicine Journalen_US
dc.subjectAntiretroviral therapyen_US
dc.subjectBiopsyen_US
dc.subjectDiagnosisen_US
dc.subjectGranulomatousen_US
dc.subjectHuman immunodeficiency virusen_US
dc.subjectLung massen_US
dc.subjectPneumocystis jiroveci pneumoniaen_US
dc.titleGranulomatous Pneumocystis jiroveci pneumonia in an HIV-positive patient on antiretroviral therapy: A diagnostic challengeen_US
dc.typeArticleen_US
dc.identifier.doi10.2174/1874306402115010019
dc.source.volume15
dc.source.issue1
dc.source.beginpage19
dc.source.endpage22


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